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Giovanna Scapin

Showing results (31-40 of 70) with videos related to

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Protein Expression and Purification|May 12, 2004
Expression, refolding, and purification of recombinant human phosphodiesterase 3B: definition of the N-terminus of the catalytic coreJeffrey P Varnerin, Christine C Chung, Sangita B Patel, et al.
Biochemistry|May 19, 2004
Crystal structure of human phosphodiesterase 3B: atomic basis for substrate and inhibitor specificityGiovanna Scapin, Sangita B Patel, Christine Chung, et al.
Bioorganic & Medicinal Chemistry Letters|September 11, 2007
Design, synthesis, and biological evaluation of triazolopiperazine-based beta-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitorsJennifer E Kowalchick, Barbara Leiting, KellyAnn D Pryor, et al.
Bioorganic & Medicinal Chemistry Letters|March 14, 2007
4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IVJoseph L Duffy, Brian A Kirk, Liping Wang, et al.
ACS Medicinal Chemistry Letters|May 19, 2016
Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 DiabetesWen-Lian Wu, Jinsong Hao, Martin Domalski, et al.
Bioorganic & Medicinal Chemistry Letters|September 14, 2007
4-arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IVDavid E Kaelin, Abigail L Smenton, George J Eiermann, et al.
Biochemistry|October 1, 2003
The structural basis for the selectivity of benzotriazole inhibitors of PTP1BGiovanna Scapin, Sangita B Patel, Joseph W Becker, et al.
Bioorganic & Medicinal Chemistry Letters|June 17, 2011
Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712Helen Chen, Timothy A Blizzard, Seongkon Kim, et al.
Bioorganic & Medicinal Chemistry Letters|April 17, 2007
Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptinTesfaye Biftu, Giovanna Scapin, Suresh Singh, et al.
Bioorganic & Medicinal Chemistry Letters|April 24, 2016
The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitorsJason M Cox, Hong D Chu, Jeffrey T Kuethe, et al.
Pageof 7

Showing results (31-40 of 70) with videos related to

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Pageof 7
Protein Expression and Purification|May 12, 2004
Expression, refolding, and purification of recombinant human phosphodiesterase 3B: definition of the N-terminus of the catalytic coreJeffrey P Varnerin, Christine C Chung, Sangita B Patel, et al.
Biochemistry|May 19, 2004
Crystal structure of human phosphodiesterase 3B: atomic basis for substrate and inhibitor specificityGiovanna Scapin, Sangita B Patel, Christine Chung, et al.
Bioorganic & Medicinal Chemistry Letters|September 11, 2007
Design, synthesis, and biological evaluation of triazolopiperazine-based beta-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitorsJennifer E Kowalchick, Barbara Leiting, KellyAnn D Pryor, et al.
Bioorganic & Medicinal Chemistry Letters|March 14, 2007
4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IVJoseph L Duffy, Brian A Kirk, Liping Wang, et al.
ACS Medicinal Chemistry Letters|May 19, 2016
Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 DiabetesWen-Lian Wu, Jinsong Hao, Martin Domalski, et al.
Bioorganic & Medicinal Chemistry Letters|September 14, 2007
4-arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IVDavid E Kaelin, Abigail L Smenton, George J Eiermann, et al.
Biochemistry|October 1, 2003
The structural basis for the selectivity of benzotriazole inhibitors of PTP1BGiovanna Scapin, Sangita B Patel, Joseph W Becker, et al.
Bioorganic & Medicinal Chemistry Letters|June 17, 2011
Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712Helen Chen, Timothy A Blizzard, Seongkon Kim, et al.
Bioorganic & Medicinal Chemistry Letters|April 17, 2007
Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptinTesfaye Biftu, Giovanna Scapin, Suresh Singh, et al.
Bioorganic & Medicinal Chemistry Letters|April 24, 2016
The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitorsJason M Cox, Hong D Chu, Jeffrey T Kuethe, et al.
Pageof 7