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Toxicological Sciences : an Official Journal of the Society of Toxicology
|
November 28, 2023
A network-based transcriptomic landscape of HepG2 cells uncovering causal gene-cytotoxicity interactions underlying drug-induced liver injury
Lukas S Wijaya, Attila Gabor, Iris E Pot, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
January 9, 2026
Quantitative Adverse Outcome Pathway Modeling of Cisplatin-Induced Nephrotoxicity: Developing In Vitro and In Vivo Models for Predictive Extrapolation
Filippo Di Tillio, Lukas Wijaya, Steven Kunnen, et al.
Liver International : Official Journal of the International Association for the Study of the Liver
|
January 13, 2024
The integrated stress response-related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability
Matthijs Vlasveld, Giulia Callegaro, Ciarán Fisher, et al.
Archives of Toxicology
|
September 26, 2019
High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability
Steven Hiemstra, Sreenivasa C Ramaiahgari, Steven Wink, et al.
Archives of Toxicology
|
November 5, 2025
A broad kinase inhibitor library live cell imaging screen using liver, kidney and cardiac hiPSC-ICAM1-eGFP reporter lineages identifies liabilities for TNFα pathway modulation
Matthijs Vlasveld, Linda van den Berk, Janet Piñero, et al.
Iscience
|
March 10, 2023
Identifying multiscale translational safety biomarkers using a network-based systems approach
Giulia Callegaro, Johannes P Schimming, Janet Piñero González, et al.
Archives of Toxicology
|
October 9, 2021
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment
Giulia Callegaro, Steven J Kunnen, Panuwat Trairatphisan, et al.
Archives of Toxicology
|
October 13, 2021
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation
Wanda van der Stel, Huan Yang, Nanette G Vrijenhoek, et al.
Archives of Toxicology
|
November 15, 2018
Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury
Ian M Copple, Wouter den Hollander, Giulia Callegaro, et al.
Iscience
|
July 21, 2025
Utilizing rat kidney gene co-expression networks to enhance safety assessment biomarker identification and human translation
Steven J Kunnen, Giulia Callegaro, Jeffrey J Sutherland, et al.
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Search research articles
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Showing results (11-20 of 22) with videos related to
Sort By:
Page
of 3
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
November 28, 2023
A network-based transcriptomic landscape of HepG2 cells uncovering causal gene-cytotoxicity interactions underlying drug-induced liver injury
Lukas S Wijaya, Attila Gabor, Iris E Pot, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
January 9, 2026
Quantitative Adverse Outcome Pathway Modeling of Cisplatin-Induced Nephrotoxicity: Developing In Vitro and In Vivo Models for Predictive Extrapolation
Filippo Di Tillio, Lukas Wijaya, Steven Kunnen, et al.
Liver International : Official Journal of the International Association for the Study of the Liver
|
January 13, 2024
The integrated stress response-related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability
Matthijs Vlasveld, Giulia Callegaro, Ciarán Fisher, et al.
Archives of Toxicology
|
September 26, 2019
High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability
Steven Hiemstra, Sreenivasa C Ramaiahgari, Steven Wink, et al.
Archives of Toxicology
|
November 5, 2025
A broad kinase inhibitor library live cell imaging screen using liver, kidney and cardiac hiPSC-ICAM1-eGFP reporter lineages identifies liabilities for TNFα pathway modulation
Matthijs Vlasveld, Linda van den Berk, Janet Piñero, et al.
Iscience
|
March 10, 2023
Identifying multiscale translational safety biomarkers using a network-based systems approach
Giulia Callegaro, Johannes P Schimming, Janet Piñero González, et al.
Archives of Toxicology
|
October 9, 2021
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment
Giulia Callegaro, Steven J Kunnen, Panuwat Trairatphisan, et al.
Archives of Toxicology
|
October 13, 2021
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation
Wanda van der Stel, Huan Yang, Nanette G Vrijenhoek, et al.
Archives of Toxicology
|
November 15, 2018
Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury
Ian M Copple, Wouter den Hollander, Giulia Callegaro, et al.
Iscience
|
July 21, 2025
Utilizing rat kidney gene co-expression networks to enhance safety assessment biomarker identification and human translation
Steven J Kunnen, Giulia Callegaro, Jeffrey J Sutherland, et al.
Page
of 3