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BMC Infectious Diseases|December 1, 2004
Pharmacokinetics of quinacrine in the treatment of prion diseaseLotus Yung, Yong Huang, Pierre Lessard, et al.International Journal of Molecular Sciences|October 23, 2019
Depicting Conformational Ensembles of α-Synuclein by Single Molecule Force Spectroscopy and Native Mass SpectroscopyRoberta Corti, Claudia A Marrano, Domenico Salerno, et al.European Journal of Medicinal Chemistry|April 24, 2020
In silico/in vitro screening and hit evaluation identified new phenothiazine anti-prion derivativesLudovica Zaccagnini, Giulia Rossetti, Thanh Hoa Tran, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 4, 2006
Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoproteinYong Huang, Hideaki Okochi, Barnaby C H May, et al.Journal of Medicinal Chemistry|January 5, 2007
Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokineticsBarnaby C H May, Julie A Zorn, Juanita Witkop, et al.Plos Pathogens|December 10, 2019
Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prionRomany Abskharon, Fei Wang, Alexandre Wohlkonig, et al.Plos One|November 22, 2017
The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion proteinGabriele Giachin, Ridvan Nepravishta, Walter Mandaliti, et al.Scientific Reports|September 8, 2017
High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prionsAlessia Franceschini, Simone Baiardi, Andrew G Hughson, et al.The Journal of Biological Chemistry|August 19, 2016
The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin DomainUrška Slapšak, Giulia Salzano, Ladan Amin, et al.Biochemistry|June 5, 2003
Copper coordination in the full-length, recombinant prion proteinColin S Burns, Eliah Aronoff-Spencer, Giuseppe Legname, et al.Pageof 24