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Giuseppina De Simone

Showing results (61-70 of 146) with videos related to

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Chemistry (Weinheim an Der Bergstrasse, Germany)|October 29, 2015
A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic AnhydrasesEmma Langella, Katia D'Ambrosio, Melissa D'Ascenzio, et al.
Biopolymers|December 31, 2013
The structural comparison between membrane-associated human carbonic anhydrases provides insights into drug design of selective inhibitorsVincenzo Alterio, Peiwen Pan, Seppo Parkkila, et al.
Journal of Medicinal Chemistry|September 2, 2005
Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme IIValeria Menchise, Giuseppina De Simone, Vincenzo Alterio, et al.
Bioorganic & Medicinal Chemistry Letters|March 23, 2005
Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme IIAnna Di Fiore, Giuseppina De Simone, Valeria Menchise, et al.
The Journal of Biological Chemistry|November 18, 2003
A substrate-induced switch in the reaction mechanism of a thermophilic esterase: kinetic evidences and structural basisGiuseppina De Simone, Luigi Mandrich, Valeria Menchise, et al.
The Biochemical Journal|January 7, 2011
C68 from the Sulfolobus islandicus plasmid-virus pSSVx is a novel member of the AbrB-like transcription factor familyPatrizia Contursi, Katia D'Ambrosio, Luciano Pirone, et al.
Bioorganic & Medicinal Chemistry|July 3, 2021
Design, synthesis and biochemical evaluation of novel carbonic anhydrase inhibitors triggered by structural knowledge on hCA VIIFrancesca Mancuso, Anna Di Fiore, Laura De Luca, et al.
Chemical Communications (Cambridge, England)|August 25, 2018
Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate bindingGiuseppina De Simone, Andrea Angeli, Murat Bozdag, et al.
Chemical Reviews|December 19, 2024
Multiple Binding Modes of Inhibitors to Human Carbonic Anhydrases: An Update on the Design of Isoform-Specific Modulators of ActivityKatia D'Ambrosio, Anna Di Fiore, Vincenzo Alterio, et al.
Journal of Enzyme Inhibition and Medicinal Chemistry|August 22, 2019
Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approachGiuseppina De Simone, Anna Di Fiore, Emanuela Truppo, et al.
Pageof 15

Showing results (61-70 of 146) with videos related to

Sort By:
Pageof 15
Chemistry (Weinheim an Der Bergstrasse, Germany)|October 29, 2015
A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic AnhydrasesEmma Langella, Katia D'Ambrosio, Melissa D'Ascenzio, et al.
Biopolymers|December 31, 2013
The structural comparison between membrane-associated human carbonic anhydrases provides insights into drug design of selective inhibitorsVincenzo Alterio, Peiwen Pan, Seppo Parkkila, et al.
Journal of Medicinal Chemistry|September 2, 2005
Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme IIValeria Menchise, Giuseppina De Simone, Vincenzo Alterio, et al.
Bioorganic & Medicinal Chemistry Letters|March 23, 2005
Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme IIAnna Di Fiore, Giuseppina De Simone, Valeria Menchise, et al.
The Journal of Biological Chemistry|November 18, 2003
A substrate-induced switch in the reaction mechanism of a thermophilic esterase: kinetic evidences and structural basisGiuseppina De Simone, Luigi Mandrich, Valeria Menchise, et al.
The Biochemical Journal|January 7, 2011
C68 from the Sulfolobus islandicus plasmid-virus pSSVx is a novel member of the AbrB-like transcription factor familyPatrizia Contursi, Katia D'Ambrosio, Luciano Pirone, et al.
Bioorganic & Medicinal Chemistry|July 3, 2021
Design, synthesis and biochemical evaluation of novel carbonic anhydrase inhibitors triggered by structural knowledge on hCA VIIFrancesca Mancuso, Anna Di Fiore, Laura De Luca, et al.
Chemical Communications (Cambridge, England)|August 25, 2018
Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate bindingGiuseppina De Simone, Andrea Angeli, Murat Bozdag, et al.
Chemical Reviews|December 19, 2024
Multiple Binding Modes of Inhibitors to Human Carbonic Anhydrases: An Update on the Design of Isoform-Specific Modulators of ActivityKatia D'Ambrosio, Anna Di Fiore, Vincenzo Alterio, et al.
Journal of Enzyme Inhibition and Medicinal Chemistry|August 22, 2019
Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approachGiuseppina De Simone, Anna Di Fiore, Emanuela Truppo, et al.
Pageof 15