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ACS Central Science|October 6, 2017
Allosteric Communication Networks in Proteins Revealed through Pocket Crosstalk AnalysisGiuseppina La Sala, Sergio Decherchi, Marco De Vivo, et al.International Journal of Molecular Sciences|February 7, 2018
Novel Bacterial Topoisomerase Inhibitors Exploit Asp83 and the Intrinsic Flexibility of the DNA Gyrase Binding SiteSebastian Franco-Ulloa, Giuseppina La Sala, Gian Pietro Miscione, et al.Proceedings of the National Academy of Sciences of the United States of America|December 31, 2025
Controlled dynamic remodeling of the spliceosome active site enables the first step of splicingGianfranco Martino, Jacopo Manigrasso, Giuseppina La Sala, et al.Journal of Chemical Information and Modeling|June 22, 2021
Unraveling the Allosteric Cross-Talk between the Coactivator Peptide and the Ligand-Binding Site in the Glucocorticoid ReceptorGiuseppina La Sala, Anders Gunnarsson, Karl Edman, et al.Journal of Chemical Theory and Computation|September 30, 2016
HRD Motif as the Central Hub of the Signaling Network for Activation Loop Autophosphorylation in Abl KinaseGiuseppina La Sala, Laura Riccardi, Roberto Gaspari, et al.Chem|August 21, 2020
Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain DisordersAnnalisa Savardi, Marco Borgogno, Roberto Narducci, et al.Journal of Medicinal Chemistry|June 13, 2017
Pharmacophore Identification and Scaffold Exploration to Discover Novel, Potent, and Chemically Stable Inhibitors of Acid Ceramidase in Melanoma CellsJose Antonio Ortega, Jose M Arencibia, Giuseppina La Sala, et al.NAR Genomics and Bioinformatics|May 4, 2026
RNAStructuromeDB: a transcriptome-wide database of predicted RNA secondary structures with integrated APIs for functional annotation and RNA-targeted drug discoveryAbdelraouf O Dapour, Jacopo Manigrasso, Warren B Rouse, et al.Biorxiv : the Preprint Server for Biology|February 23, 2026
Conformational dynamics at the pre-miR-377 Dicer site governs selective small-molecule recognitionJacopo Manigrasso, Emeline Mestdach, Riccardo Quaia, et al.Chemical Science|June 30, 2023
Combining structural and coevolution information to unveil allosteric sitesGiuseppina La Sala, Christopher Pfleger, Helena Käck, et al.Pageof 2