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Nature Medicine|June 13, 2018
A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockadeDaniela S Thommen, Viktor H Koelzer, Petra Herzig, et al.Nature Immunology|October 30, 2025
Cancer suppresses mitochondrial chaperone activity in macrophages to drive immune evasionHaoxin Zhao, Jaeoh Park, Yuzhu Wang, et al.Nature Immunology|May 25, 2021
Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunityYugang Guo, Yu-Qing Xie, Min Gao, et al.Nature Immunology|October 6, 2020
Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustionYi-Ru Yu, Hana Imrichova, Haiping Wang, et al.Nature Immunology|February 19, 2020
CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumorsHaiping Wang, Fabien Franco, Yao-Chen Tsui, et al.Cell|September 1, 2015
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell ResponsesPing-Chih Ho, Jessica Dauz Bihuniak, Andrew N Macintyre, et al.Science Immunology|May 1, 2026
Citraconate preserves T cell stemness and antitumor immunityWenhui Li, Minmin Ge, Ziyi Luo, et al.Nature Metabolism|March 5, 2025
Asparagine deprivation enhances T cell antitumour response in patients via ROS-mediated metabolic and signal adaptationsHsuan-Chia Chang, Chung-Ying Tsai, Cheng-Lung Hsu, et al.Nature|February 15, 2021
CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumoursRoberta Zappasodi, Inna Serganova, Ivan J Cohen, et al.Journal for Immunotherapy of Cancer|October 12, 2019
Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cellsBeatris Mastelic-Gavillet, Blanca Navarro Rodrigo, Laure Décombaz, et al.Pageof 16