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ACS Medicinal Chemistry Letters|August 16, 2023
Discovery of the TLR7/8 Antagonist MHV370 for Treatment of Systemic Autoimmune DiseasesPhil Alper, Claudia Betschart, Cédric André, et al.ACS Medicinal Chemistry Letters|April 22, 2022
Structure-Based Optimization of a Fragment-like TLR8 Binding Screening Hit to an In Vivo Efficacious TLR7/8 AntagonistClaudia Betschart, Michael Faller, Florence Zink, et al.Journal of Medicinal Chemistry|June 27, 2025
Discovery and Optimization of Selective Inhibitors of Large Tumor Suppressor Kinases LATS1 and 2 for In Vivo Investigation of the Hippo-YAP Pathway in Tissue RegenerationKenji Namoto, Eric Vangrevelinghe, Rainer Machauer, et al.Cell Stem Cell|April 5, 2024
NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivoKenji Namoto, Clara Baader, Vanessa Orsini, et al.Pageof 2