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Organic Letters|August 31, 2002
Synthesis of enantiopure dihydropyranones: aldol-based ring expansion of dihydrofuransTimothy J Donohoe, Ali Raoof, Graeme C Freestone, et al.
Tetrahedron|July 8, 2010
New synthetic technology for the construction of N-hydroxyindoles and synthesis of nocathiacin I model systemsK C Nicolaou, Anthony A Estrada, Graeme C Freestone, et al.
RSC Advances|July 29, 2024
Towards combining backbone and sugar constraint in 3'-3' bis-phosphonate tethered 2'-4' bridged LNA oligonucleotide trimersEdouard Duchamp, Guillermo Vasquez, Neda Firoozi, et al.
Organic Letters|August 28, 2004
Enantioselective partial reduction of 2,5-disubstituted pyrroles via a chiral protonation approachTimothy J Donohoe, Graeme C Freestone, Catherine E Headley, et al.
The Journal of Organic Chemistry|March 1, 2023
Systematic Investigation of Tether Length and Phosphorus Configuration in Backbone Constrained Macrocyclic Nucleic Acids to Modulate Binding Kinetics for RNATamilselvan Rajasekaran, Graeme C Freestone, Rodrigo Galindo-Murillo, et al.
ACS Omega|November 17, 2025
Synthesis, Incorporation, and Translation Properties of Threose Nucleic Acid Modified Trinucleotide Cap AnalogsAlexander Pontarelli, Guillermo Vasquez, Wuxia Fu, et al.
Journal of the American Chemical Society|January 18, 2022
Backbone Hydrocarbon-Constrained Nucleic Acids Modulate Hybridization Kinetics for RNATamilselvan Rajasekaran, Graeme C Freestone, Rodrigo Galindo-Murillo, et al.
Nucleic Acids Research|February 5, 2021
Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOsGuillermo Vasquez, Graeme C Freestone, W Brad Wan, et al.
Nucleic Acids Research|August 21, 2021
Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotidesBrooke A Anderson, Graeme C Freestone, Audrey Low, et al.
Nucleic Acids Research|April 10, 2025
Conjugation to a transferrin receptor 1-binding Bicycle peptide enhances ASO and siRNA potency in skeletal and cardiac musclesMichael E Østergaard, Michele Carrer, Brooke A Anderson, et al.
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