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Graeme Semple

Showing results (21-30 of 51) with videos related to

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Bioorganic & Medicinal Chemistry Letters|November 20, 2016
Tetrahydroquinoline-based tricyclic amines as potent and selective agonists of the 5-HT<sub>2C</sub> receptorThomas O Schrader, Michelle Kasem, Albert Ren, et al.
Bioorganic & Medicinal Chemistry Letters|February 14, 2012
Identification of fused bicyclic heterocycles as potent and selective 5-HT(2A) receptor antagonists for the treatment of insomniaYifeng Xiong, Brett Ullman, Jin-Sun Karoline Choi, et al.
Bioorganic & Medicinal Chemistry Letters|September 7, 2007
Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109aPhilip J Skinner, Martin C Cherrier, Peter J Webb, et al.
Bioorganic & Medicinal Chemistry Letters|January 19, 2020
Discovery of a lead series of potent benzodiazepine 5-HT<sub>2C</sub> receptor agonists with high selectivity in functional and binding assaysAlbert Ren, Xiuwen Zhu, Konrad Feichtinger, et al.
Journal of Medicinal Chemistry|May 14, 2025
Diazepine Agonists of the 5-HT<sub>2C</sub> Receptor with Unprecedented Selectivity: Discovery of Bexicaserin (LP352)Albert Ren, Xiuwen Zhu, Juerg Lehmann, et al.
Bioorganic & Medicinal Chemistry Letters|February 26, 2021
Novel (R)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,n]naphthyridines as potent and selective agonists of the 5-HT<sub>2C</sub> receptorThomas O Schrader, Xiuwen Zhu, Michelle Kasem, et al.
Bioorganic & Medicinal Chemistry Letters|February 11, 2015
Discovery of a new series of potent prostacyclin receptor agonists with in vivo activity in ratThuy-Anh Tran, Young-Jun Shin, Bryan Kramer, et al.
Bioorganic & Medicinal Chemistry Letters|September 24, 2009
Pyrimidine-based antagonists of h-MCH-R1 derived from ATC0175: in vitro profiling and in vivo evaluationGraeme Semple, Thuy-Anh Tran, Bryan Kramer, et al.
Bioorganic & Medicinal Chemistry Letters|August 12, 2009
Solubilized phenyl-pyrazole ureas as potent, selective 5-HT(2A) inverse-agonists and their application as antiplatelet agentsPeter I Dosa, Sonja Strah-Pleynet, Honnappa Jayakumar, et al.
Bioorganic & Medicinal Chemistry Letters|April 6, 2010
Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a)P Douglas Boatman, Thomas O Schrader, Michelle Kasem, et al.
Pageof 6

Showing results (21-30 of 51) with videos related to

Sort By:
Pageof 6
Bioorganic & Medicinal Chemistry Letters|November 20, 2016
Tetrahydroquinoline-based tricyclic amines as potent and selective agonists of the 5-HT<sub>2C</sub> receptorThomas O Schrader, Michelle Kasem, Albert Ren, et al.
Bioorganic & Medicinal Chemistry Letters|February 14, 2012
Identification of fused bicyclic heterocycles as potent and selective 5-HT(2A) receptor antagonists for the treatment of insomniaYifeng Xiong, Brett Ullman, Jin-Sun Karoline Choi, et al.
Bioorganic & Medicinal Chemistry Letters|September 7, 2007
Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109aPhilip J Skinner, Martin C Cherrier, Peter J Webb, et al.
Bioorganic & Medicinal Chemistry Letters|January 19, 2020
Discovery of a lead series of potent benzodiazepine 5-HT<sub>2C</sub> receptor agonists with high selectivity in functional and binding assaysAlbert Ren, Xiuwen Zhu, Konrad Feichtinger, et al.
Journal of Medicinal Chemistry|May 14, 2025
Diazepine Agonists of the 5-HT<sub>2C</sub> Receptor with Unprecedented Selectivity: Discovery of Bexicaserin (LP352)Albert Ren, Xiuwen Zhu, Juerg Lehmann, et al.
Bioorganic & Medicinal Chemistry Letters|February 26, 2021
Novel (R)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,n]naphthyridines as potent and selective agonists of the 5-HT<sub>2C</sub> receptorThomas O Schrader, Xiuwen Zhu, Michelle Kasem, et al.
Bioorganic & Medicinal Chemistry Letters|February 11, 2015
Discovery of a new series of potent prostacyclin receptor agonists with in vivo activity in ratThuy-Anh Tran, Young-Jun Shin, Bryan Kramer, et al.
Bioorganic & Medicinal Chemistry Letters|September 24, 2009
Pyrimidine-based antagonists of h-MCH-R1 derived from ATC0175: in vitro profiling and in vivo evaluationGraeme Semple, Thuy-Anh Tran, Bryan Kramer, et al.
Bioorganic & Medicinal Chemistry Letters|August 12, 2009
Solubilized phenyl-pyrazole ureas as potent, selective 5-HT(2A) inverse-agonists and their application as antiplatelet agentsPeter I Dosa, Sonja Strah-Pleynet, Honnappa Jayakumar, et al.
Bioorganic & Medicinal Chemistry Letters|April 6, 2010
Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a)P Douglas Boatman, Thomas O Schrader, Michelle Kasem, et al.
Pageof 6