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Regulatory Toxicology and Pharmacology : RTP|December 11, 2024
Control of N-nitrosamine impurities in drug products: Progressing the current CPCA framework and supporting the derivation of robust compound specific acceptable intakesDavid J Ponting, Andreas Czich, Susan P Felter, et al.Journal of Pharmaceutical Sciences|October 7, 2023
Revisiting the Landscape of Potential Small and Drug Substance Related Nitrosamines in PharmaceuticalsMichael J Burns, David J Ponting, Robert S Foster, et al.Journal of Pharmaceutical Sciences|November 19, 2022
The Landscape of Potential Small and Drug Substance Related Nitrosamines in PharmaceuticalsJoerg Schlingemann, Michael J Burns, David J Ponting, et al.SLAS Discovery : Advancing Life Sciences R & D|September 12, 2018
Identification of G-Quadruplex-Binding Inhibitors of Myc Expression through Affinity Selection-Mass SpectrometryDeborah A Flusberg, Noreen F Rizvi, Victoria Kutilek, et al.Molecular Pharmaceutics|April 12, 2022
Prediction of In Vivo Pharmacokinetic Parameters and Time-Exposure Curves in Rats Using Machine Learning from the Chemical StructureOlga Obrezanova, Anton Martinsson, Tom Whitehead, et al.Bioorganic & Medicinal Chemistry Letters|October 27, 2006
Structure-activity relationships of novel non-competitive mGluR1 antagonists: a potential treatment for chronic painDafydd R Owen, Peter G Dodd, Simon Gayton, et al.Bioorganic & Medicinal Chemistry Letters|September 26, 2015
Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modificationsJongwon Lim, Michael D Altman, James Baker, et al.Nature|March 31, 2022
Targeting Xist with compounds that disrupt RNA structure and X inactivationRodrigo Aguilar, Kerrie B Spencer, Barry Kesner, et al.Bioorganic & Medicinal Chemistry Letters|September 30, 2011
Discovery of a series of potent and selective human H4 antagonists using ligand efficiency and libraries to explore structure-activity relationship (SAR)M Abid Masood, Matthew D Selby, Andrew S Bell, et al.Chemical Research in Toxicology|February 5, 2024
Mechanisms of Nitrosamine Mutagenicity and Their Relationship to Rodent Carcinogenic PotencyDavid J Snodin, Alejandra Trejo-Martin, David J Ponting, et al.Pageof 3