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Antimicrobial Agents and Chemotherapy
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March 10, 2022
Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones
Gregory S Basarab, Sandeep Ghorpade, Liezl Gibhard, et al.
Journal of Medicinal Chemistry
|
June 25, 2014
Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099)
Gregory S Basarab, Pamela J Hill, C Edwin Garner, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
November 5, 2014
Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome
Nelson B Olivier, Roger B Altman, Jonas Noeske, et al.
Journal of Medicinal Chemistry
|
May 12, 2025
Cell-Based Progression of Spiroindoline Phenotypic Hits Leads to the Identification of Compounds with Diverging Parasitological Profiles against the Human Malaria Parasite <i>Plasmodium falciparum</i>
Jean Dam, Grant A Boyle, André Horatscheck, et al.
Journal of Medicinal Chemistry
|
October 7, 2025
Optimization of 2,8-Diaryl-1,5-naphthyridines as <i>Plasmodium falciparum</i> Phosphatidylinositol 4-Kinase Inhibitors with Improved ADME Profiles and In Vivo Efficacy
Godwin A Dziwornu, Donald Seanego, Stephen Fienberg, et al.
Scientific Reports
|
July 15, 2015
Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases
Gregory S Basarab, Gunther H Kern, John McNulty, et al.
Journal of Medicinal Chemistry
|
February 11, 2026
Identification of Compound <b>15</b> (MMV1581361) as a <i>Pf</i>ATP4 Inhibitor with Transmission-Blocking Activity and <i>In Vivo</i> Efficacy in a SCID Mouse Model of Malaria
Henry A Onyame, Stephen Brand, Delphin Baud, et al.
Journal of Medicinal Chemistry
|
October 26, 2020
Identification of 2,4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and <i>In Vivo</i> Efficacy in the <i>Plasmodium falciparum</i> NSG Mouse Model
André Horatscheck, Ana Andrijevic, Aloysius T Nchinda, et al.
Journal of Medicinal Chemistry
|
August 20, 2021
1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in <i>Mycobacterium tuberculosis</i>
Lutete Peguy Khonde, Rudolf Müller, Grant A Boyle, et al.
Journal of Medicinal Chemistry
|
January 4, 2021
Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies
Candice Soares de Melo, Vinayak Singh, Alissa Myrick, et al.
Page
of 5
Search research articles
Search
Showing results (31-40 of 43) with videos related to
Sort By:
Page
of 5
Antimicrobial Agents and Chemotherapy
|
March 10, 2022
Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones
Gregory S Basarab, Sandeep Ghorpade, Liezl Gibhard, et al.
Journal of Medicinal Chemistry
|
June 25, 2014
Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099)
Gregory S Basarab, Pamela J Hill, C Edwin Garner, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
November 5, 2014
Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome
Nelson B Olivier, Roger B Altman, Jonas Noeske, et al.
Journal of Medicinal Chemistry
|
May 12, 2025
Cell-Based Progression of Spiroindoline Phenotypic Hits Leads to the Identification of Compounds with Diverging Parasitological Profiles against the Human Malaria Parasite <i>Plasmodium falciparum</i>
Jean Dam, Grant A Boyle, André Horatscheck, et al.
Journal of Medicinal Chemistry
|
October 7, 2025
Optimization of 2,8-Diaryl-1,5-naphthyridines as <i>Plasmodium falciparum</i> Phosphatidylinositol 4-Kinase Inhibitors with Improved ADME Profiles and In Vivo Efficacy
Godwin A Dziwornu, Donald Seanego, Stephen Fienberg, et al.
Scientific Reports
|
July 15, 2015
Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases
Gregory S Basarab, Gunther H Kern, John McNulty, et al.
Journal of Medicinal Chemistry
|
February 11, 2026
Identification of Compound <b>15</b> (MMV1581361) as a <i>Pf</i>ATP4 Inhibitor with Transmission-Blocking Activity and <i>In Vivo</i> Efficacy in a SCID Mouse Model of Malaria
Henry A Onyame, Stephen Brand, Delphin Baud, et al.
Journal of Medicinal Chemistry
|
October 26, 2020
Identification of 2,4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and <i>In Vivo</i> Efficacy in the <i>Plasmodium falciparum</i> NSG Mouse Model
André Horatscheck, Ana Andrijevic, Aloysius T Nchinda, et al.
Journal of Medicinal Chemistry
|
August 20, 2021
1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in <i>Mycobacterium tuberculosis</i>
Lutete Peguy Khonde, Rudolf Müller, Grant A Boyle, et al.
Journal of Medicinal Chemistry
|
January 4, 2021
Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies
Candice Soares de Melo, Vinayak Singh, Alissa Myrick, et al.
Page
of 5