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Bioconjugate Chemistry
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September 9, 2017
Attachment Site Cysteine Thiol pK<sub>a</sub> Is a Key Driver for Site-Dependent Stability of THIOMAB Antibody-Drug Conjugates
Breanna S Vollmar, Binqing Wei, Rachana Ohri, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
October 8, 2013
Dual targeting of HER2-positive cancer with trastuzumab emtansine and pertuzumab: critical role for neuregulin blockade in antitumor response to combination therapy
Gail D Lewis Phillips, Carter T Fields, Guangmin Li, et al.
Journal of the American Chemical Society
|
July 1, 2024
On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to Therapy
Pragya Adhikari, Guangmin Li, MaryAnn Go, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
September 1, 2010
Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2-positive breast cancer
Jagath R Junutula, Kelly M Flagella, Richard A Graham, et al.
Cancer Research
|
November 18, 2008
Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate
Gail D Lewis Phillips, Guangmin Li, Debra L Dugger, et al.
Cancer Research
|
September 18, 2014
Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells
Teemu T Junttila, Ji Li, Jennifer Johnston, et al.
Journal of Medicinal Chemistry
|
August 14, 2020
Systematic Variation of Pyrrolobenzodiazepine (PBD)-Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody-Drug Conjugates
Leanna R Staben, Jinhua Chen, Josefa Dela Cruz-Chuh, et al.
Journal of Medicinal Chemistry
|
November 8, 2017
Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers
Stephen J Gregson, Luke A Masterson, Binqing Wei, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
January 23, 2003
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship
Dirk B Mendel, A Douglas Laird, Xiaohua Xin, et al.
Bioconjugate Chemistry
|
June 22, 2017
Development of Efficient Chemistry to Generate Site-Specific Disulfide-Linked Protein- and Peptide-Payload Conjugates: Application to THIOMAB Antibody-Drug Conjugates
Jack D Sadowsky, Thomas H Pillow, Jinhua Chen, et al.
Page
of 4
Search research articles
Search
Showing results (21-30 of 35) with videos related to
Sort By:
Page
of 4
Bioconjugate Chemistry
|
September 9, 2017
Attachment Site Cysteine Thiol pK<sub>a</sub> Is a Key Driver for Site-Dependent Stability of THIOMAB Antibody-Drug Conjugates
Breanna S Vollmar, Binqing Wei, Rachana Ohri, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
October 8, 2013
Dual targeting of HER2-positive cancer with trastuzumab emtansine and pertuzumab: critical role for neuregulin blockade in antitumor response to combination therapy
Gail D Lewis Phillips, Carter T Fields, Guangmin Li, et al.
Journal of the American Chemical Society
|
July 1, 2024
On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to Therapy
Pragya Adhikari, Guangmin Li, MaryAnn Go, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
September 1, 2010
Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2-positive breast cancer
Jagath R Junutula, Kelly M Flagella, Richard A Graham, et al.
Cancer Research
|
November 18, 2008
Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate
Gail D Lewis Phillips, Guangmin Li, Debra L Dugger, et al.
Cancer Research
|
September 18, 2014
Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells
Teemu T Junttila, Ji Li, Jennifer Johnston, et al.
Journal of Medicinal Chemistry
|
August 14, 2020
Systematic Variation of Pyrrolobenzodiazepine (PBD)-Dimer Payload Physicochemical Properties Impacts Efficacy and Tolerability of the Corresponding Antibody-Drug Conjugates
Leanna R Staben, Jinhua Chen, Josefa Dela Cruz-Chuh, et al.
Journal of Medicinal Chemistry
|
November 8, 2017
Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers
Stephen J Gregson, Luke A Masterson, Binqing Wei, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
January 23, 2003
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship
Dirk B Mendel, A Douglas Laird, Xiaohua Xin, et al.
Bioconjugate Chemistry
|
June 22, 2017
Development of Efficient Chemistry to Generate Site-Specific Disulfide-Linked Protein- and Peptide-Payload Conjugates: Application to THIOMAB Antibody-Drug Conjugates
Jack D Sadowsky, Thomas H Pillow, Jinhua Chen, et al.
Page
of 4