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Guifen Xu

Showing results (11-20 of 25) with videos related to

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Xenobiotica; the Fate of Foreign Compounds in Biological Systems|March 24, 2015
Pharmacokinetics and metabolism of AMG 232, a novel orally bioavailable inhibitor of the MDM2-p53 interaction, in rats, dogs and monkeys: in vitro-in vivo correlationQiuping Ye, Min Jiang, Wotang T Huang, et al.
Bioanalysis|September 6, 2012
Application of DBS sampling in combination with LC-MS/MS for pharmacokinetic evaluation of a compound with species-specific blood-to-plasma partitioningGuifen Xu, Jiyun S Chen, Ruta Phadnis, et al.
Journal of Pharmacokinetics and Pharmacodynamics|October 20, 2014
FLT3 and CDK4/6 inhibitors: signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemiaYaping Zhang, Cheng-Pang Hsu, Jian-Feng Lu, et al.
Journal of Medicinal Chemistry|June 11, 2015
A selective prostaglandin E2 receptor subtype 2 (EP2) antagonist increases the macrophage-mediated clearance of amyloid-beta plaquesBrian M Fox, Hilary P Beck, Philip M Roveto, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 20, 2011
Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH)Xiaoshan Min, Stephen T Thibault, Amy C Porter, et al.
The Journal of Biological Chemistry|January 17, 2009
Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivoAlykhan Motani, Zhulun Wang, Marion Conn, et al.
Bioorganic & Medicinal Chemistry Letters|March 12, 2011
Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitorsDarin J Gustin, Zhihua Ma, Xiaoshan Min, et al.
Bioorganic & Medicinal Chemistry Letters|July 3, 2010
Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazinesJacob A Kaizerman, Wade Aaron, Songzhu An, et al.
Journal of Medicinal Chemistry|January 5, 2021
Discovery of Potent and Selective Methylenephosphonic Acid CD73 InhibitorsEhesan U Sharif, Jaroslaw Kalisiak, Kenneth V Lawson, et al.
Bioorganic & Medicinal Chemistry Letters|August 16, 2011
Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hitMatthew L Brown, Wade Aaron, Richard J Austin, et al.
Pageof 3

Showing results (11-20 of 25) with videos related to

Sort By:
Pageof 3
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|March 24, 2015
Pharmacokinetics and metabolism of AMG 232, a novel orally bioavailable inhibitor of the MDM2-p53 interaction, in rats, dogs and monkeys: in vitro-in vivo correlationQiuping Ye, Min Jiang, Wotang T Huang, et al.
Bioanalysis|September 6, 2012
Application of DBS sampling in combination with LC-MS/MS for pharmacokinetic evaluation of a compound with species-specific blood-to-plasma partitioningGuifen Xu, Jiyun S Chen, Ruta Phadnis, et al.
Journal of Pharmacokinetics and Pharmacodynamics|October 20, 2014
FLT3 and CDK4/6 inhibitors: signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemiaYaping Zhang, Cheng-Pang Hsu, Jian-Feng Lu, et al.
Journal of Medicinal Chemistry|June 11, 2015
A selective prostaglandin E2 receptor subtype 2 (EP2) antagonist increases the macrophage-mediated clearance of amyloid-beta plaquesBrian M Fox, Hilary P Beck, Philip M Roveto, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 20, 2011
Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH)Xiaoshan Min, Stephen T Thibault, Amy C Porter, et al.
The Journal of Biological Chemistry|January 17, 2009
Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivoAlykhan Motani, Zhulun Wang, Marion Conn, et al.
Bioorganic & Medicinal Chemistry Letters|March 12, 2011
Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitorsDarin J Gustin, Zhihua Ma, Xiaoshan Min, et al.
Bioorganic & Medicinal Chemistry Letters|July 3, 2010
Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazinesJacob A Kaizerman, Wade Aaron, Songzhu An, et al.
Journal of Medicinal Chemistry|January 5, 2021
Discovery of Potent and Selective Methylenephosphonic Acid CD73 InhibitorsEhesan U Sharif, Jaroslaw Kalisiak, Kenneth V Lawson, et al.
Bioorganic & Medicinal Chemistry Letters|August 16, 2011
Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hitMatthew L Brown, Wade Aaron, Richard J Austin, et al.
Pageof 3