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Journal of Medicinal Chemistry|April 27, 2013
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitorsXiaozhang Zheng, Paul Bauer, Timm Baumeister, et al.Journal of Medicinal Chemistry|February 17, 2012
Potent and selective aminopyrimidine-based B-Raf inhibitors with favorable physicochemical and pharmacokinetic propertiesSimon Mathieu, Stefan N Gradl, Li Ren, et al.Journal of Medicinal Chemistry|January 11, 2014
Fragment-based identification of amides derived from trans-2-(pyridin-3-yl)cyclopropanecarboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)Anthony M Giannetti, Xiaozhang Zheng, Nicholas J Skelton, et al.Bioorganic & Medicinal Chemistry Letters|January 4, 2015
Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubilityMark Zak, Bianca M Liederer, Deepak Sampath, et al.Journal of Medicinal Chemistry|July 18, 2013
Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitorsXiaozhang Zheng, Paul Bauer, Timm Baumeister, et al.Journal of Medicinal Chemistry|May 23, 2025
Discovery of AB801, a Potent and Selective Inhibitor of AXL Receptor Tyrosine Kinase for Use in Cancer TherapyDillon H Miles, Manjunath Lamani, Srinivas Reddy Paladugu, et al.Bioorganic & Medicinal Chemistry Letters|April 15, 2019
Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signalingMark Zak, Emily J Hanan, Patrick Lupardus, et al.Bioorganic & Medicinal Chemistry Letters|May 15, 2013
Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition propertiesJanet Gunzner-Toste, Guiling Zhao, Paul Bauer, et al.Journal of Medicinal Chemistry|December 12, 2017
Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease SpecificityBinQing Wei, Janet Gunzner-Toste, Hui Yao, et al.Journal of Medicinal Chemistry|September 19, 2012
Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitorsAnthony A Estrada, Xingrong Liu, Charles Baker-Glenn, et al.Pageof 15