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Journal of Medicinal Chemistry|February 13, 2023
From (Tool)Bench to Bedside: The Potential of Necroptosis InhibitorsChristopher R Gardner, Katherine A Davies, Ying Zhang, et al.
Blood|August 25, 2018
Humanized Mcl-1 mice enable accurate preclinical evaluation of MCL-1 inhibitors destined for clinical useMargs S Brennan, Catherine Chang, Lin Tai, et al.
Cellular Microbiology|October 27, 2016
Analysis of Ca2+ mediated signaling regulating Toxoplasma infectivity reveals complex relationships between key moleculesRebecca J Stewart, Lachlan Whitehead, Brunda Nijagal, et al.
The Journal of Biological Chemistry|September 4, 2009
Conformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligandsErinna F Lee, Peter E Czabotar, Hong Yang, et al.
Oncogene|May 11, 2018
Dual inhibition of BCL-XL and MCL-1 is required to induce tumour regression in lung squamous cell carcinomas sensitive to FGFR inhibitionClare E Weeden, Casey Ah-Cann, Aliaksei Z Holik, et al.
Autophagy|May 13, 2016
BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic activity and has only minimal effects on autophagic fluxBoris Reljic, Stephanie Conos, Erinna F Lee, et al.
Cell Death & Disease|July 7, 2017
The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XLAlex Rd Delbridge, Brandon J Aubrey, Craig Hyland, et al.
Proteomics|May 20, 2024
Improved drug target deconvolution with PISA-DIA using an extended, overlapping temperature gradientSamantha J Emery-Corbin, Jumana M Yousef, Subash Adhikari, et al.
Cancer Biology & Therapy|January 17, 2004
The Tyr-kinase inhibitor AG879, that blocks the ETK-PAK1 interaction, suppresses the RAS-induced PAK1 activation and malignant transformationHong He, Yumiko Hirokawa, Aviv Gazit, et al.
Cell Death and Differentiation|October 1, 2016
Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIMLeona Rohrbeck, Jia-Nan Gong, Erinna F Lee, et al.
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