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The Biochemical Journal|November 14, 2013
Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKLJames M Murphy, Isabelle S Lucet, Joanne M Hildebrand, et al.
Blood|July 29, 2016
Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1Jia-Nan Gong, Tiffany Khong, David Segal, et al.
Blood Advances|October 5, 2020
BCL-XL inhibition by BH3-mimetic drugs induces apoptosis in models of Epstein-Barr virus-associated T/NK-cell lymphomaNenad Sejic, Lindsay C George, Rosemary J Tierney, et al.
Cell|December 20, 2014
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN productionMichael J White, Kate McArthur, Donald Metcalf, et al.
Cancer Cell|April 12, 2017
Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer ProgressionAshleigh R Poh, Christopher G Love, Frederick Masson, et al.
Nature Communications|July 23, 2024
Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escapeXinyu Wu, Margareta Go, Julie V Nguyen, et al.
Brain Research|December 3, 2014
Dual role of Src kinase in governing neuronal survivalM Iqbal Hossain, Ashfaqul Hoque, Guillaume Lessene, et al.
Plos Pathogens|September 5, 2025
Divergent resistance pathways amongst SARS-CoV-2 PLpro inhibitors highlight the need for scaffold diversityXinyu Wu, Shane M Devine, Margareta Go, et al.
Plos Biology|May 2, 2024
Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosisZheng Yuan, Mark F van Delft, Mark Xiang Li, et al.
Journal of Medicinal Chemistry|April 27, 2021
Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-XL and BCL-2Michael J Roy, Amelia Vom, Toru Okamoto, et al.
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