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The EMBO Journal|November 25, 2020
BCL-XL exerts a protective role against anemia caused by radiation-induced kidney damageKerstin Brinkmann, Paul Waring, Stefan P Glaser, et al.Nature Communications|June 5, 2019
Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutationsRichard W Birkinshaw, Jia-Nan Gong, Cindy S Luo, et al.Cell Death and Differentiation|March 25, 2022
BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cellsDiane Moujalled, Adam G Southon, Eiman Saleh, et al.Chemmedchem|March 29, 2014
Simplified silvestrol analogues with potent cytotoxic activityBill C Hawkins, Lisa M Lindqvist, Duong Nhu, et al.Cell Death & Disease|September 11, 2020
Defining the susceptibility of colorectal cancers to BH3-mimetic compoundsMing-Jie Luo, Michelle Palmieri, Chris D Riffkin, et al.Journal of Medicinal Chemistry|January 25, 2014
De-novo designed library of benzoylureas as inhibitors of BCL-XL: synthesis, structural and biochemical characterizationRyan M Brady, Amelia Vom, Michael J Roy, et al.Nature Communications|November 23, 2021
Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosisYanxiang Meng, Katherine A Davies, Cheree Fitzgibbon, et al.Nature Microbiology|August 31, 2016
Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosisMary Speir, Kate E Lawlor, Stefan P Glaser, et al.Cell Death & Disease|April 2, 2022
The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKLAnnette V Jacobsen, Catia L Pierotti, Kym N Lowes, et al.Nature Communications|May 29, 2026
The benchmarking and application of tag-degraders in vivo to validate therapeutic targetsCharlene M Magtoto, Stephen Mieruszynski, Hao Dong, et al.Pageof 9