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Nature Communications|April 20, 2022
Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platformsChristoph Grohmann, Charlene M Magtoto, Joel R Walker, et al.Cell Death and Differentiation|April 9, 2025
Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteinsJia-Nan Gong, Tirta M Djajawi, Donia M Moujalled, et al.Chemmedchem|December 15, 2020
Synthesis and Biological Evaluation of (-) and (+)-Spiroleucettadine and AnaloguesMichael P Badart, Emma M Barnes, Andrew P Cording, et al.Nature Chemical Biology|April 23, 2013
Structure-guided design of a selective BCL-X(L) inhibitorGuillaume Lessene, Peter E Czabotar, Brad E Sleebs, et al.Proceedings of the National Academy of Sciences of the United States of America|October 8, 2014
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell deathJoanne M Hildebrand, Maria C Tanzer, Isabelle S Lucet, et al.Science Advances|March 5, 2025
Differential regulation of BAX and BAK apoptotic activity revealed by small moleculesKaiming Li, Yu Q Yap, Donia M Moujalled, et al.Blood|October 11, 2022
Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemiaDonia M Moujalled, Fiona C Brown, Chong Chyn Chua, et al.Journal of Medicinal Chemistry|June 18, 2013
Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XLBrad E Sleebs, Wilhemus J A Kersten, Sanji Kulasegaram, et al.ACS Chemical Biology|September 9, 2020
Potent Inhibition of Necroptosis by Simultaneously Targeting Multiple Effectors of the PathwayCatia L Pierotti, Maria C Tanzer, Annette V Jacobsen, et al.Leukemia|September 15, 2018
Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemiaDonia M Moujalled, Giovanna Pomilio, Corina Ghiurau, et al.Pageof 9