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Biomolecules|September 28, 2023
Mitochondrial Calcium Overload Plays a Causal Role in Oxidative Stress in the Failing HeartHaikel Dridi, Gaetano Santulli, Laith Bahlouli, et al.
Nature Communications|September 15, 2024
Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disordersMarco C Miotto, Steven Reiken, Anetta Wronska, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 13, 2025
Targeting ryanodine receptors with allopurinol and xanthine derivatives for the treatment of cardiac and musculoskeletal weakness disordersMarco C Miotto, Estefania Luna-Figueroa, Carl Tchagou, et al.
Science Advances|July 20, 2022
Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatmentMarco C Miotto, Gunnar Weninger, Haikel Dridi, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 25, 2024
Structural insights into the regulation of RyR1 by S100A1Gunnar Weninger, Marco C Miotto, Carl Tchagou, et al.
The Journal of Clinical Investigation|December 15, 2025
Structural basis for simvastatin-induced skeletal muscle weakness associated with type 1 ryanodine receptor T4709M mutationGunnar Weninger, Haikel Dridi, Steven Reiken, et al.
Circulation Research|January 25, 2021
Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in CardiomyocytesJonas Peper, Daniel Kownatzki-Danger, Gunnar Weninger, et al.
Journal of Molecular and Cellular Cardiology|July 3, 2024
Targeting calpain-2-mediated junctophilin-2 cleavage delays heart failure progression following myocardial infarctionSatadru K Lahiri, Jiao Lu, Yuriana Aguilar-Sanchez, et al.
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