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BMC Medicine
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March 5, 2024
TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro
Qing-Qing Duan, Han Wang, Wei-Ming Su, et al.
Chemical Biology & Drug Design
|
July 31, 2017
Structure-based discovery of new selective small-molecule sirtuin 5 inhibitors
Sha Liu, Sen Ji, Zhu-Jun Yu, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society
|
August 16, 2025
Co-delivery of SN38 and SR717 activates cGAS-STING for near-infrared II image-guided chemoimmunotherapy
Xiaowen Hou, Chunlin Ren, Xiaodong Zeng, et al.
European Journal of Medicinal Chemistry
|
May 20, 2023
Metal binding pharmacophore click-derived discovery of new broad-spectrum metallo-β-lactamase inhibitors
Yu-Hang Yan, Hao-Sheng Ding, Kai-Rong Zhu, et al.
Bioorganic Chemistry
|
March 30, 2023
New ε-N-thioglutaryl-lysine derivatives as SIRT5 inhibitors: Chemical synthesis, kinetic and crystallographic studies
Ji Deng, Ze-Min Liu, Kai-Rong Zhu, et al.
Chemical Communications (Cambridge, England)
|
July 14, 2021
Design and enantioselective synthesis of 3-(α-acrylic acid) benzoxaboroles to combat carbapenemase resistance
You-Cai Xiao, Xiao-Pan Chen, Ji Deng, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2026
Structural Optimization of Benzyl-5-methyl‑1<i>H</i>‑Imidazole Derivatives as Human Glutaminyl Cyclase Inhibitors
Yu-Ting Chen, Fan-Bo Meng, Yu-Qing Zhuang, et al.
Journal of Medicinal Chemistry
|
February 1, 2013
Structure-activity relationship studies of pyrazolo[3,4-d]pyrimidine derivatives leading to the discovery of a novel multikinase inhibitor that potently inhibits FLT3 and VEGFR2 and evaluation of its activity against acute myeloid leukemia in vitro and in vivo
Ling-Ling Yang, Guo-Bo Li, Shuang Ma, et al.
Journal of Chemical Information and Modeling
|
May 14, 2025
Deciphering Glutaminyl Cyclase Catalytic Pathways Enables Recognition of Anchor Pharmacophores for Inhibitor Discovery
Jing-Wei Wu, Xiang-Li Ning, Biao-Dan Tang, et al.
Journal of Medicinal Chemistry
|
May 17, 2026
X-ray Crystallography-Guided Discovery of a Potent Dual-Pocket Competitive SIRT5 Inhibitor against Sepsis-Associated AKI
Yingying Jiang, Lina Yang, Rui Xiong, et al.
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Search research articles
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Showing results (51-60 of 79) with videos related to
Sort By:
Page
of 8
BMC Medicine
|
March 5, 2024
TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro
Qing-Qing Duan, Han Wang, Wei-Ming Su, et al.
Chemical Biology & Drug Design
|
July 31, 2017
Structure-based discovery of new selective small-molecule sirtuin 5 inhibitors
Sha Liu, Sen Ji, Zhu-Jun Yu, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society
|
August 16, 2025
Co-delivery of SN38 and SR717 activates cGAS-STING for near-infrared II image-guided chemoimmunotherapy
Xiaowen Hou, Chunlin Ren, Xiaodong Zeng, et al.
European Journal of Medicinal Chemistry
|
May 20, 2023
Metal binding pharmacophore click-derived discovery of new broad-spectrum metallo-β-lactamase inhibitors
Yu-Hang Yan, Hao-Sheng Ding, Kai-Rong Zhu, et al.
Bioorganic Chemistry
|
March 30, 2023
New ε-N-thioglutaryl-lysine derivatives as SIRT5 inhibitors: Chemical synthesis, kinetic and crystallographic studies
Ji Deng, Ze-Min Liu, Kai-Rong Zhu, et al.
Chemical Communications (Cambridge, England)
|
July 14, 2021
Design and enantioselective synthesis of 3-(α-acrylic acid) benzoxaboroles to combat carbapenemase resistance
You-Cai Xiao, Xiao-Pan Chen, Ji Deng, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2026
Structural Optimization of Benzyl-5-methyl‑1<i>H</i>‑Imidazole Derivatives as Human Glutaminyl Cyclase Inhibitors
Yu-Ting Chen, Fan-Bo Meng, Yu-Qing Zhuang, et al.
Journal of Medicinal Chemistry
|
February 1, 2013
Structure-activity relationship studies of pyrazolo[3,4-d]pyrimidine derivatives leading to the discovery of a novel multikinase inhibitor that potently inhibits FLT3 and VEGFR2 and evaluation of its activity against acute myeloid leukemia in vitro and in vivo
Ling-Ling Yang, Guo-Bo Li, Shuang Ma, et al.
Journal of Chemical Information and Modeling
|
May 14, 2025
Deciphering Glutaminyl Cyclase Catalytic Pathways Enables Recognition of Anchor Pharmacophores for Inhibitor Discovery
Jing-Wei Wu, Xiang-Li Ning, Biao-Dan Tang, et al.
Journal of Medicinal Chemistry
|
May 17, 2026
X-ray Crystallography-Guided Discovery of a Potent Dual-Pocket Competitive SIRT5 Inhibitor against Sepsis-Associated AKI
Yingying Jiang, Lina Yang, Rui Xiong, et al.
Page
of 8