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Guo-Bo Li

Showing results (71-80 of 79) with videos related to

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Chemical Communications (Cambridge, England)|May 5, 2017
Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibitionGuo-Bo Li, Jürgen Brem, Robert Lesniak, et al.
Medchemcomm|February 19, 2019
Crystallographic and SAR analyses reveal the high requirements needed to selectively and potently inhibit SIRT2 deacetylase and decanoylaseLing-Ling Yang, Wei Xu, Jie Yan, et al.
Briefings in Bioinformatics|July 16, 2025
A 3D pocket-aware lead optimization model with knowledge guidance and its application for discovery of new glutaminyl cyclase inhibitorsAnjie Qiao, Yuting Chen, Junjie Xie, et al.
Journal of Medicinal Chemistry|October 4, 2023
Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-β-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate BindingYu-Hang Yan, Ting-Ting Zhang, Rong Li, et al.
Journal of Medicinal Chemistry|August 9, 2023
Structure-Activity Relationship Studies of 2,4,5-Trisubstituted Pyrimidine Derivatives Leading to the Identification of a Novel and Potent Sirtuin 5 Inhibitor against Sepsis-Associated Acute Kidney InjuryLuohe Mou, Lina Yang, Shuyan Hou, et al.
Journal of Medicinal Chemistry|July 4, 2019
Structure-Based Development of (1-(3'-Mercaptopropanamido)methyl)boronic Acid Derived Broad-Spectrum, Dual-Action Inhibitors of Metallo- and Serine-β-lactamasesYao-Ling Wang, Sha Liu, Zhu-Jun Yu, et al.
Journal of Medicinal Chemistry|August 19, 2016
Drug Discovery against Psoriasis: Identification of a New Potent FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor, 1-(4-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)oxy)-3-fluorophenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea, That Showed Potent Activity in a Psoriatic Animal ModelGuo-Bo Li, Shuang Ma, Ling-Ling Yang, et al.
Journal of Medicinal Chemistry|April 4, 2015
Design, Synthesis, and Structure-Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast CancerChun-Hui Zhang, Ming-Wu Zheng, Ya-Ping Li, et al.
Journal of Medicinal Chemistry|June 10, 2021
X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's DiseaseXiang-Li Ning, Yu-Zhi Li, Cui Huo, et al.
Pageof 8

Showing results (71-80 of 79) with videos related to

Sort By:
Pageof 8
You have reached the last page of results.This site can display upto 79 results.
Chemical Communications (Cambridge, England)|May 5, 2017
Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibitionGuo-Bo Li, Jürgen Brem, Robert Lesniak, et al.
Medchemcomm|February 19, 2019
Crystallographic and SAR analyses reveal the high requirements needed to selectively and potently inhibit SIRT2 deacetylase and decanoylaseLing-Ling Yang, Wei Xu, Jie Yan, et al.
Briefings in Bioinformatics|July 16, 2025
A 3D pocket-aware lead optimization model with knowledge guidance and its application for discovery of new glutaminyl cyclase inhibitorsAnjie Qiao, Yuting Chen, Junjie Xie, et al.
Journal of Medicinal Chemistry|October 4, 2023
Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-β-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate BindingYu-Hang Yan, Ting-Ting Zhang, Rong Li, et al.
Journal of Medicinal Chemistry|August 9, 2023
Structure-Activity Relationship Studies of 2,4,5-Trisubstituted Pyrimidine Derivatives Leading to the Identification of a Novel and Potent Sirtuin 5 Inhibitor against Sepsis-Associated Acute Kidney InjuryLuohe Mou, Lina Yang, Shuyan Hou, et al.
Journal of Medicinal Chemistry|July 4, 2019
Structure-Based Development of (1-(3'-Mercaptopropanamido)methyl)boronic Acid Derived Broad-Spectrum, Dual-Action Inhibitors of Metallo- and Serine-β-lactamasesYao-Ling Wang, Sha Liu, Zhu-Jun Yu, et al.
Journal of Medicinal Chemistry|August 19, 2016
Drug Discovery against Psoriasis: Identification of a New Potent FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor, 1-(4-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)oxy)-3-fluorophenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea, That Showed Potent Activity in a Psoriatic Animal ModelGuo-Bo Li, Shuang Ma, Ling-Ling Yang, et al.
Journal of Medicinal Chemistry|April 4, 2015
Design, Synthesis, and Structure-Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast CancerChun-Hui Zhang, Ming-Wu Zheng, Ya-Ping Li, et al.
Journal of Medicinal Chemistry|June 10, 2021
X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's DiseaseXiang-Li Ning, Yu-Zhi Li, Cui Huo, et al.
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