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Journal of Clinical Pharmacology|April 23, 2024
Characterizing the Nonlinear Pharmacokinetics and Pharmacodynamics of BI 187004, an 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, in Humans by a Target-Mediated Drug Disposition ModelXuanzhen Yuan, Guohua AnJournal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|December 23, 2014
Quantification of 5,7-dimethoxyflavone in mouse plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and its application to a pharmacokinetic studyDi Bei, Guohua AnJournal of Pharmaceutical and Biomedical Analysis|December 15, 2015
Pharmacokinetics and tissue distribution of 5,7-dimethoxyflavone in mice following single dose oral administrationDi Bei, Guohua AnJournal of Pharmacokinetics and Pharmacodynamics|April 22, 2021
Comparing the performance of first-order conditional estimation (FOCE) and different expectation-maximization (EM) methods in NONMEM: real data experience with complex nonlinear parent-metabolite pharmacokinetic modelThanh Bach, Guohua AnBiopharmaceutics & Drug Disposition|June 11, 2010
Effects of the isoflavonoid biochanin A on the transport of mitoxantrone in vitro and in vivoGuohua An, Marilyn E MorrisThe AAPS Journal|March 28, 2012
A physiologically based pharmacokinetic model of mitoxantrone in mice and scale-up to humans: a semi-mechanistic model incorporating DNA and protein bindingGuohua An, Marilyn E MorrisBiopharmaceutics & Drug Disposition|September 13, 2011
The sulfated conjugate of biochanin A is a substrate of breast cancer resistant protein (ABCG2)Guohua An, Marilyn E MorrisPharmaceutical Research|April 7, 2010
Effects of single and multiple flavonoids on BCRP-mediated accumulation, cytotoxicity and transport of mitoxantrone in vitroGuohua An, Marilyn E MorrisJournal of Clinical Pharmacology|December 8, 2022
Importance of Target-Mediated Drug Disposition (TMDD) of Small-Molecule Compounds and Its Impact on Drug Development-Example of the Class Effect of HSD-1 InhibitorsGuohua An, David A KatzJournal of Pharmaceutical and Biomedical Analysis|October 24, 2009
HPLC analysis of mitoxantrone in mouse plasma and tissues: application in a pharmacokinetic studyGuohua An, Marilyn E MorrisPageof 9