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Journal of Pharmacokinetics and Pharmacodynamics|November 14, 2022
Pharmacometric model of agalsidase-migalastat interaction in human: a novel mechanistic model of drug-drug interaction between a therapeutic protein and a small moleculeThanh Bach, Nan Wu, Guohua AnThe AAPS Journal|October 29, 2024
Exploring the Impact of Pharmacological Target-Mediated Low Plasma Exposure in Lead Compound Selection in Drug Discovery - A Modeling ApproachMin Xu, Duxin Sun, Guohua AnJournal of Clinical Pharmacology|May 2, 2015
Small-molecule compounds exhibiting target-mediated drug disposition - A case example of ABT-384Guohua An, Wei Liu, Sandeep DuttaClinical Pharmacokinetics|July 15, 2023
Population Target-Mediated Pharmacokinetic/Pharmacodynamic Modeling to Evaluate SPI-62 Exposure and Hepatic 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD-1) Inhibition in Healthy AdultsNan Wu, David A Katz, Guohua AnPharmaceutical Research|February 1, 2011
5,7-Dimethoxyflavone and multiple flavonoids in combination alter the ABCG2-mediated tissue distribution of mitoxantrone in miceGuohua An, Fang Wu, Marilyn E MorrisAntimicrobial Agents and Chemotherapy|April 15, 2015
Limited sampling strategy and target attainment analysis for levofloxacin in patients with tuberculosisAbdullah Alsultan, Guohua An, Charles A PeloquinDrug Metabolism and Disposition: the Biological Fate of Chemicals|July 9, 2014
Flavonoids are inhibitors of human organic anion transporter 1 (OAT1)-mediated transportGuohua An, Xiaodong Wang, Marilyn E MorrisJournal of Clinical Pharmacology|June 10, 2021
A Target-Mediated Drug Disposition Model to Explain Nonlinear Pharmacokinetics of the 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor SPI-62 in Healthy AdultsNan Wu, David A Katz, Guohua AnDrug Metabolism and Disposition: the Biological Fate of Chemicals|December 9, 2010
The bioflavonoid kaempferol is an Abcg2 substrate and inhibits Abcg2-mediated quercetin effluxGuohua An, Jorge Gallegos, Marilyn E MorrisJournal of Pharmaceutical Sciences|June 5, 2019
Nilotinib Alters the Efflux Transporter-Mediated Pharmacokinetics of Afatinib in MiceRonilda R D'Cunha, Daryl J Murry, Guohua AnPageof 9