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Oncogene|February 1, 2022
Overcoming acquired resistance to third-generation EGFR inhibitors by targeting activation of intrinsic apoptotic pathway through Mcl-1 inhibition, Bax activation, or bothGuangzhi Ma, Yunfu Deng, Luxi Qian, et al.Theranostics|August 10, 2021
Discovery of Small Molecule Bak Activator for Lung Cancer TherapyDongkyoo Park, Abu Syed Md Anisuzzaman, Andrew T Magis, et al.Cancer Research|July 22, 2021
Targeting c-Myc to Overcome Acquired Resistance of EGFR Mutant NSCLC Cells to the Third-Generation EGFR Tyrosine Kinase Inhibitor, OsimertinibLei Zhu, Zhen Chen, Hongjing Zang, et al.Cancer Letters|July 25, 2016
Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatmentPuyu Shi, You-Take Oh, Guojing Zhang, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|August 3, 2017
Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 DegradationPuyu Shi, You-Take Oh, Liang Deng, et al.Therapeutic Advances in Medical Oncology|March 11, 2015
Anaplastic lymphoma kinase (ALK) gene alteration in signet ring cell carcinoma of the gastrointestinal tractOlatunji B Alese, Bassel F El-Rayes, Gabriel Sica, et al.Journal for Immunotherapy of Cancer|January 11, 2021
Durvalumab and tremelimumab with or without stereotactic body radiation therapy in relapsed small cell lung cancer: a randomized phase II studySuchita Pakkala, Kristin Higgins, Zhengjia Chen, et al.Molecular Cell|December 19, 2017
The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung CancerLingtao Jin, Jaemoo Chun, Chaoyun Pan, et al.Cancer Cell|May 26, 2015
Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer TherapyBingshe Han, Dongkyoo Park, Rui Li, et al.Journal of Translational Medicine|May 5, 2016
Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancerTaofeek K Owonikoko, Guojing Zhang, Hyun S Kim, et al.Pageof 6