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Guyan Liang

Showing results (1-10 of 13) with videos related to

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Current Topics in Medicinal Chemistry|September 16, 2015
Development of Trypsin-Like Serine Protease Inhibitors as Therapeutic Agents: Opportunities, Challenges, and their Unique Structure-Based RationalesGuyan Liang, J Phillip Bowen
Chirality|February 9, 2002
Molecular mechanics (MM4) force field development for phosphine and its alkyl derivativesPatricia Metthe Todebush, Guyan Liang, J Phillip Bowen
Bioorganic & Medicinal Chemistry Letters|March 6, 2012
Human kallikrein 6 inhibitors with a para-amidobenzylanmine P1 group identified through virtual screeningGuyan Liang, Xin Chen, Suzanne Aldous, et al.
Bioorganic & Medicinal Chemistry Letters|September 3, 2004
Novel pyrazinone inhibitors of mast cell tryptase: synthesis and SAR evaluationCorey Hopkins, Kent Neuenschwander, Anthony Scotese, et al.
Bioorganic & Medicinal Chemistry Letters|January 24, 2012
A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinityGuyan Liang, Yong Mi Choi-Sledeski, Patrick Shum, et al.
Bioorganic & Medicinal Chemistry Letters|April 10, 2012
Dimerization of β-tryptase inhibitors, does it work for both basic and neutral P1 groups?Guyan Liang, Yong Mi Choi-Sledeski, Xin Chen, et al.
Bioorganic & Medicinal Chemistry Letters|December 24, 2011
Structure-based library design and the discovery of a potent and selective mast cell β-tryptase inhibitor as an oral therapeutic agentGuyan Liang, Suzanne Aldous, Gregory Merriman, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Virtual Screening and X-ray Crystallography for Human Kallikrein 6 Inhibitors with an Amidinothiophene P1 GroupGuyan Liang, Xin Chen, Suzanne Aldous, et al.
Bioorganic & Medicinal Chemistry Letters|September 22, 2010
A conformationally constrained inhibitor with an enhanced potency for β-tryptase and stability against semicarbazide-sensitive amine oxidase (SSAO)Guyan Liang, Yong Mi Choi-Sledeski, Gregory Poli, et al.
Bioorganic & Medicinal Chemistry Letters|May 25, 2005
Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptaseCorey R Hopkins, Mark Czekaj, Steven S Kaye, et al.
Pageof 2

Showing results (1-10 of 13) with videos related to

Sort By:
Pageof 2
Current Topics in Medicinal Chemistry|September 16, 2015
Development of Trypsin-Like Serine Protease Inhibitors as Therapeutic Agents: Opportunities, Challenges, and their Unique Structure-Based RationalesGuyan Liang, J Phillip Bowen
Chirality|February 9, 2002
Molecular mechanics (MM4) force field development for phosphine and its alkyl derivativesPatricia Metthe Todebush, Guyan Liang, J Phillip Bowen
Bioorganic & Medicinal Chemistry Letters|March 6, 2012
Human kallikrein 6 inhibitors with a para-amidobenzylanmine P1 group identified through virtual screeningGuyan Liang, Xin Chen, Suzanne Aldous, et al.
Bioorganic & Medicinal Chemistry Letters|September 3, 2004
Novel pyrazinone inhibitors of mast cell tryptase: synthesis and SAR evaluationCorey Hopkins, Kent Neuenschwander, Anthony Scotese, et al.
Bioorganic & Medicinal Chemistry Letters|January 24, 2012
A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinityGuyan Liang, Yong Mi Choi-Sledeski, Patrick Shum, et al.
Bioorganic & Medicinal Chemistry Letters|April 10, 2012
Dimerization of β-tryptase inhibitors, does it work for both basic and neutral P1 groups?Guyan Liang, Yong Mi Choi-Sledeski, Xin Chen, et al.
Bioorganic & Medicinal Chemistry Letters|December 24, 2011
Structure-based library design and the discovery of a potent and selective mast cell β-tryptase inhibitor as an oral therapeutic agentGuyan Liang, Suzanne Aldous, Gregory Merriman, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Virtual Screening and X-ray Crystallography for Human Kallikrein 6 Inhibitors with an Amidinothiophene P1 GroupGuyan Liang, Xin Chen, Suzanne Aldous, et al.
Bioorganic & Medicinal Chemistry Letters|September 22, 2010
A conformationally constrained inhibitor with an enhanced potency for β-tryptase and stability against semicarbazide-sensitive amine oxidase (SSAO)Guyan Liang, Yong Mi Choi-Sledeski, Gregory Poli, et al.
Bioorganic & Medicinal Chemistry Letters|May 25, 2005
Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptaseCorey R Hopkins, Mark Czekaj, Steven S Kaye, et al.
Pageof 2