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Frontiers in Cell and Developmental Biology|March 27, 2026
PRMT5 inhibition triggers functional ATM deficiency and sensitizes pancreatic cancer to CHK1 blockadeMadeline Dzikowski, Gareth Pollin, Veda Gunia, et al.
Critical Reviews in Oncology/Hematology|August 17, 2025
The mitochondrial catastrophe induced by NUPR1 inhibitors as a novel strategy to fight against cancerJuan Iovanna, Jose Luis Neira, Olga Abian, et al.
Plos One|December 10, 2016
Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte ExpansionNidhi Jalan-Sakrikar, Thiago M De Assuncao, Jie Lu, et al.
Scientific Reports|November 20, 2018
Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosisPatricia Santofimia-Castaño, Wenjun Lan, Jennifer Bintz, et al.
The Journal of Clinical Investigation|September 25, 2014
IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylationMaria Noé Garcia, Daniel Grasso, Maria Belen Lopez-Millan, et al.
Epigenomes|March 27, 2026
Mutant KRAS Heterogeneity Shapes Nuclear Architecture During Pancreatic Cancer InitiationGareth Pollin, Angela J Mathison, Elise N Leverence, et al.
Journal of Cellular Physiology|April 23, 2015
Functional Characterization of Nupr1L, A Novel p53-Regulated Isoform of the High-Mobility Group (HMG)-Related Protumoral Protein Nupr1Maria Belen Lopez, Maria Noé Garcia, Daniel Grasso, et al.
The Journal of Biological Chemistry|April 25, 2014
New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipidsThiago M de Assuncao, Gwen Lomberk, Sheng Cao, et al.
Ebiomedicine|April 16, 2021
Metabolomic profiling of pancreatic adenocarcinoma reveals key features driving clinical outcome and drug resistanceAbdessamad El Kaoutari, Nicolas A Fraunhoffer, Owen Hoare, et al.
Computational and Structural Biotechnology Journal|November 13, 2023
A multi-layered computational structural genomics approach enhances domain-specific interpretation of Kleefstra syndrome variants in EHMT1Young-In Chi, Salomão D Jorge, Davin R Jensen, et al.
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