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Gyorgy Snell

Showing results (11-20 of 63) with videos related to

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Bioorganic & Medicinal Chemistry|October 1, 2016
Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitorsYasuhiro Imaeda, Michiko Tawada, Shinkichi Suzuki, et al.
Bioorganic & Medicinal Chemistry|May 15, 2018
Discovery of benzimidazole derivatives as orally active renin inhibitors: Optimization of 3,5-disubstituted piperidine to improve pharmacokinetic profileHidekazu Tokuhara, Yasuhiro Imaeda, Yoshiyuki Fukase, et al.
Bioorganic & Medicinal Chemistry|April 28, 2016
Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKCθ inhibitorsTaisuke Katoh, Takafumi Takai, Takafumi Yukawa, et al.
The Journal of Biological Chemistry|July 29, 2003
Crystal structure of Pasteurella haemolytica ferric ion-binding protein A reveals a novel class of bacterial iron-binding proteinsStephen R Shouldice, Douglas R Dougan, Pamela A Williams, et al.
The Journal of Biological Chemistry|April 2, 2011
Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 proteinKathleen Aertgeerts, Robert Skene, Jason Yano, et al.
Bioorganic & Medicinal Chemistry Letters|September 28, 2011
Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitorsTohru Yamashita, Makoto Kamata, Satoshi Endo, et al.
Science (New York, N.Y.)|June 28, 2022
Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolutionTyler N Starr, Allison J Greaney, William W Hannon, et al.
Bioorganic & Medicinal Chemistry|January 3, 2018
Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitorsAkira Kaieda, Masashi Takahashi, Takafumi Takai, et al.
Bioorganic & Medicinal Chemistry|August 2, 2017
Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug designTakeshi Yasui, Takeshi Yamamoto, Nozomu Sakai, et al.
Science Translational Medicine|January 11, 2022
Predicting the mutational drivers of future SARS-CoV-2 variants of concernM Cyrus Maher, Istvan Bartha, Steven Weaver, et al.
Pageof 7

Showing results (11-20 of 63) with videos related to

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Pageof 7
Bioorganic & Medicinal Chemistry|October 1, 2016
Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitorsYasuhiro Imaeda, Michiko Tawada, Shinkichi Suzuki, et al.
Bioorganic & Medicinal Chemistry|May 15, 2018
Discovery of benzimidazole derivatives as orally active renin inhibitors: Optimization of 3,5-disubstituted piperidine to improve pharmacokinetic profileHidekazu Tokuhara, Yasuhiro Imaeda, Yoshiyuki Fukase, et al.
Bioorganic & Medicinal Chemistry|April 28, 2016
Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKCθ inhibitorsTaisuke Katoh, Takafumi Takai, Takafumi Yukawa, et al.
The Journal of Biological Chemistry|July 29, 2003
Crystal structure of Pasteurella haemolytica ferric ion-binding protein A reveals a novel class of bacterial iron-binding proteinsStephen R Shouldice, Douglas R Dougan, Pamela A Williams, et al.
The Journal of Biological Chemistry|April 2, 2011
Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 proteinKathleen Aertgeerts, Robert Skene, Jason Yano, et al.
Bioorganic & Medicinal Chemistry Letters|September 28, 2011
Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitorsTohru Yamashita, Makoto Kamata, Satoshi Endo, et al.
Science (New York, N.Y.)|June 28, 2022
Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolutionTyler N Starr, Allison J Greaney, William W Hannon, et al.
Bioorganic & Medicinal Chemistry|January 3, 2018
Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitorsAkira Kaieda, Masashi Takahashi, Takafumi Takai, et al.
Bioorganic & Medicinal Chemistry|August 2, 2017
Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug designTakeshi Yasui, Takeshi Yamamoto, Nozomu Sakai, et al.
Science Translational Medicine|January 11, 2022
Predicting the mutational drivers of future SARS-CoV-2 variants of concernM Cyrus Maher, Istvan Bartha, Steven Weaver, et al.
Pageof 7