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Journal of Medicinal Chemistry
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August 18, 2016
Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177)
George V De Lucca, Qing Shi, Qingjie Liu, et al.
Journal of Medicinal Chemistry
|
August 28, 2015
Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist
James A Monn, Lourdes Prieto, Lorena Taboada, et al.
Medchemcomm
|
August 16, 2018
Identification of potent tricyclic prodrug S1P<sub>1</sub> receptor modulators
David Marcoux, Hai-Yun Xiao, T G Murali Dhar, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist
Robert J Cherney, Lyndon A M Cornelius, Anurag Srivastava, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 14, 2017
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
Hua Gong, David S Weinstein, Zhonghui Lu, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Asymmetric Hydroboration Approach to the Scalable Synthesis of ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986104) as a Potent S1P<sub>1</sub> Receptor Modulator
Michael G Yang, Zili Xiao, T G Murali Dhar, et al.
ACS Medicinal Chemistry Letters
|
November 20, 2020
Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK
Anurag S Srivastava, Soo Ko, Scott H Watterson, et al.
G3 (Bethesda, Md.)
|
November 9, 2021
Development of the Wheat Practical Haplotype Graph database as a resource for genotyping data storage and genotype imputation
Katherine W Jordan, Peter J Bradbury, Zachary R Miller, et al.
Journal of Medicinal Chemistry
|
February 21, 2019
Identification and Preclinical Pharmacology of ((1 R,3 S)-1-Amino-3-(( S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P<sub>1</sub>) Modulator Advanced into Clinical Trials
John L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.
Nature Communications
|
April 23, 2026
Small RNA genomics of Aedes aegypti mosquitoes discovers infectious viruses that trigger an RNA interference response
Shruti Gupta, Rohit Sharma, Adeline E Williams, et al.
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of 88
Search research articles
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Showing results (851-860 of 872) with videos related to
Sort By:
Page
of 88
Journal of Medicinal Chemistry
|
August 18, 2016
Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177)
George V De Lucca, Qing Shi, Qingjie Liu, et al.
Journal of Medicinal Chemistry
|
August 28, 2015
Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist
James A Monn, Lourdes Prieto, Lorena Taboada, et al.
Medchemcomm
|
August 16, 2018
Identification of potent tricyclic prodrug S1P<sub>1</sub> receptor modulators
David Marcoux, Hai-Yun Xiao, T G Murali Dhar, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist
Robert J Cherney, Lyndon A M Cornelius, Anurag Srivastava, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 14, 2017
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
Hua Gong, David S Weinstein, Zhonghui Lu, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Asymmetric Hydroboration Approach to the Scalable Synthesis of ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986104) as a Potent S1P<sub>1</sub> Receptor Modulator
Michael G Yang, Zili Xiao, T G Murali Dhar, et al.
ACS Medicinal Chemistry Letters
|
November 20, 2020
Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK
Anurag S Srivastava, Soo Ko, Scott H Watterson, et al.
G3 (Bethesda, Md.)
|
November 9, 2021
Development of the Wheat Practical Haplotype Graph database as a resource for genotyping data storage and genotype imputation
Katherine W Jordan, Peter J Bradbury, Zachary R Miller, et al.
Journal of Medicinal Chemistry
|
February 21, 2019
Identification and Preclinical Pharmacology of ((1 R,3 S)-1-Amino-3-(( S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P<sub>1</sub>) Modulator Advanced into Clinical Trials
John L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.
Nature Communications
|
April 23, 2026
Small RNA genomics of Aedes aegypti mosquitoes discovers infectious viruses that trigger an RNA interference response
Shruti Gupta, Rohit Sharma, Adeline E Williams, et al.
Page
of 88