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Journal of Medicinal Chemistry
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October 12, 2016
Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P<sub>1</sub>) Employing Ligand-Based Drug Design
Hai-Yun Xiao, Scott H Watterson, Charles M Langevine, et al.
Journal of Medicinal Chemistry
|
January 21, 2015
Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures
James A Monn, Lourdes Prieto, Lorena Taboada, et al.
ACS Medicinal Chemistry Letters
|
July 18, 2020
Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis
Satheesh Nair, Sreekantha Ratna Kumar, Venkatram Reddy Paidi, et al.
Journal of Medicinal Chemistry
|
March 21, 2019
Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK)
Scott H Watterson, Qingjie Liu, Myra Beaudoin Bertrand, et al.
Parasites & Vectors
|
March 4, 2024
A genotyping array for the globally invasive vector mosquito, Aedes albopictus
Luciano Veiga Cosme, Margaret Corley, Thomas Johnson, et al.
Annals of Surgery Open : Perspectives of Surgical History, Education, and Clinical Approaches
|
August 21, 2023
Design of a Novel Online, Modular, Flipped-classroom Surgical Curriculum for East, Central, and Southern Africa
Andrea S Parker, Katherine A Hill, Bruce C Steffes, et al.
Journal of Medicinal Chemistry
|
September 2, 2016
Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton's Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers
Scott H Watterson, George V De Lucca, Qing Shi, et al.
Journal of Medicinal Chemistry
|
October 23, 2019
Rationally Designed, Conformationally Constrained Inverse Agonists of RORγt-Identification of a Potent, Selective Series with Biologic-Like in Vivo Efficacy
David Marcoux, James J-W Duan, Qing Shi, et al.
Journal of Medicinal Chemistry
|
May 26, 2017
Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological Disorders
Qingjie Liu, Qing Shi, David Marcoux, et al.
Genome Announcements
|
November 18, 2017
Genome Sequences of Four Subcluster L2 <i>Mycobacterium</i> Phages, Finemlucis, Miley16, Wilder, and Zakai
Christopher D Herren, Alexandra Peister, Timothy S Breton, et al.
Page
of 88
Search research articles
Search
Showing results (861-870 of 872) with videos related to
Sort By:
Page
of 88
Journal of Medicinal Chemistry
|
October 12, 2016
Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P<sub>1</sub>) Employing Ligand-Based Drug Design
Hai-Yun Xiao, Scott H Watterson, Charles M Langevine, et al.
Journal of Medicinal Chemistry
|
January 21, 2015
Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures
James A Monn, Lourdes Prieto, Lorena Taboada, et al.
ACS Medicinal Chemistry Letters
|
July 18, 2020
Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis
Satheesh Nair, Sreekantha Ratna Kumar, Venkatram Reddy Paidi, et al.
Journal of Medicinal Chemistry
|
March 21, 2019
Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK)
Scott H Watterson, Qingjie Liu, Myra Beaudoin Bertrand, et al.
Parasites & Vectors
|
March 4, 2024
A genotyping array for the globally invasive vector mosquito, Aedes albopictus
Luciano Veiga Cosme, Margaret Corley, Thomas Johnson, et al.
Annals of Surgery Open : Perspectives of Surgical History, Education, and Clinical Approaches
|
August 21, 2023
Design of a Novel Online, Modular, Flipped-classroom Surgical Curriculum for East, Central, and Southern Africa
Andrea S Parker, Katherine A Hill, Bruce C Steffes, et al.
Journal of Medicinal Chemistry
|
September 2, 2016
Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton's Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers
Scott H Watterson, George V De Lucca, Qing Shi, et al.
Journal of Medicinal Chemistry
|
October 23, 2019
Rationally Designed, Conformationally Constrained Inverse Agonists of RORγt-Identification of a Potent, Selective Series with Biologic-Like in Vivo Efficacy
David Marcoux, James J-W Duan, Qing Shi, et al.
Journal of Medicinal Chemistry
|
May 26, 2017
Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological Disorders
Qingjie Liu, Qing Shi, David Marcoux, et al.
Genome Announcements
|
November 18, 2017
Genome Sequences of Four Subcluster L2 <i>Mycobacterium</i> Phages, Finemlucis, Miley16, Wilder, and Zakai
Christopher D Herren, Alexandra Peister, Timothy S Breton, et al.
Page
of 88