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Molecular Cancer Therapeutics|December 23, 2011
Low-dose metronomic oral dosing of a prodrug of gemcitabine (LY2334737) causes antitumor effects in the absence of inhibition of systemic vasculogenesisGiulio Francia, Yuval Shaked, Kae Hashimoto, et al.
International Journal of Cancer|January 5, 2002
A very early induction of major vault protein accompanied by increased drug resistance in U-937 cellsYi Hu, Andrew G Stephen, Jin Cao, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 12, 2012
Pharmacogenomics of gemcitabine metabolism: functional analysis of genetic variants in cytidine deaminase and deoxycytidine kinaseJessica A Roseberry Baker, Enaksha R Wickremsinhe, Claire H Li, et al.
Biochemical Pharmacology|March 10, 2004
Evaluation of the binding of the tricyclic isoxazole photoaffinity label LY475776 to multidrug resistance associated protein 1 (MRP1) orthologs and several ATP- binding cassette (ABC) drug transportersAnne H Dantzig, Robert L Shepard, Susan E Pratt, et al.
Molecular Pharmacology|April 19, 2002
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoproteinSean Ekins, Richard B Kim, Brenda F Leake, et al.
Bioorganic & Medicinal Chemistry Letters|December 28, 1999
Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146B H Norman, A H Dantzig, J S Kroin, et al.
Molecular Pharmacology|April 19, 2002
Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substratesSean Ekins, Richard B Kim, Brenda F Leake, et al.
Bioorganic & Medicinal Chemistry Letters|April 18, 2002
Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1)Bryan H Norman, Joseph M Gruber, Sean P Hollinshead, et al.
Bioorganic & Medicinal Chemistry Letters|October 6, 2005
Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1)Bryan H Norman, Peter A Lander, Joseph M Gruber, et al.
Advances in Enzyme Regulation|January 1, 1997
Pharmacological characterization of LY335979: a potent cyclopropyldibenzosuberane modulator of P-glycoproteinJ J Starling, R L Shepard, J Cao, et al.
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