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Biochemical Pharmacology|June 2, 2009
Effect of P-glycoprotein-mediated efflux on cerebrospinal fluid concentrations in rhesus monkeysCuyue Tang, Yuhsin Kuo, Nicole T Pudvah, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|December 1, 2005
Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transportM Yamazaki, B Li, S W Louie, et al.
Journal of Pharmacological and Toxicological Methods|March 21, 2006
Development and characterization of LLC-PK1 cells containing Sprague-Dawley rat Abcb1a (Mdr1a): comparison of rat P-glycoprotein transport to human and mouseCatherine L Booth-Genthe, Steven W Louie, Edward J Carlini, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 1, 1996
Species and organ differences in first-pass metabolism of the ester prodrug L-751,164 in dogs and monkeys. In vivo and in vitro studiesT Prueksaritanont, L M Gorham, J D Ellis, et al.
Molecular Pharmacology|March 24, 2011
RNA-induced silencing complex-bound small interfering RNA is a determinant of RNA interference-mediated gene silencing in miceJie Wei, Jeffrey Jones, Jing Kang, et al.
Bioorganic & Medicinal Chemistry Letters|September 11, 2007
Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitorsKeith P Moore, Hong Zhu, Hemaka A Rajapakse, et al.
Bioorganic & Medicinal Chemistry Letters|January 30, 2007
Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformationShaun R Stauffer, Matthew G Stanton, Alison R Gregro, et al.
Bioorganic & Medicinal Chemistry Letters|May 8, 2007
Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitorsStacey R Lindsley, Keith P Moore, Hemaka A Rajapakse, et al.
Bioorganic & Medicinal Chemistry Letters|October 10, 2006
Identification of novel, orally bioavailable spirohydantoin CGRP receptor antagonistsIan M Bell, Rodney A Bednar, John F Fay, et al.
Pharmaceutical Research|July 2, 2014
siRNA-mediated knockdown of P450 oxidoreductase in rats: a tool to reduce metabolism by CYPs and increase exposure of high clearance compoundsRob S Burke, Inthirai Somasuntharam, Paul Rearden, et al.
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