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Journal of Immunological Methods|June 20, 2017
A systematic study of the effect of low pH acid treatment on anti-drug antibodies specific for a domain antibody therapeutic: Impact on drug tolerance, assay sensitivity and post-validation method assessment of ADA in clinical serum samplesUma Kavita, Jia Duo, Sean M Crawford, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|March 11, 2015
Development and validation of a liquid chromatography tandem mass spectrometry assay for the quantitation of a protein therapeutic in cynomolgus monkey serumYue Zhao, Guowen Liu, Aida Angeles, et al.
Journal of Immunological Methods|December 3, 2014
Development and characterization of a pre-treatment procedure to eliminate human monoclonal antibody therapeutic drug and matrix interference in cell-based functional neutralizing antibody assaysWeifeng Xu, Hao Jiang, Craig Titsch, et al.
Bioanalysis|November 12, 2014
Development and validation of an LC-MS/MS assay for the quantitation of a PEGylated anti-CD28 domain antibody in human serum: overcoming interference from antidrug antibodies and soluble targetChao Gong, Jianing Zeng, Billy Akinsanya, et al.
Analytical Chemistry|February 11, 2014
Innovative use of LC-MS/MS for simultaneous quantitation of neutralizing antibody, residual drug, and human immunoglobulin G in immunogenicity assay developmentHao Jiang, Weifeng Xu, Craig A Titsch, et al.
Analytical Chemistry|September 13, 2013
Fully validated LC-MS/MS assay for the simultaneous quantitation of coadministered therapeutic antibodies in cynomolgus monkey serumHao Jiang, Jianing Zeng, Craig Titsch, et al.
JCI Insight|September 20, 2016
In vivo disruption of latent HSV by designer endonuclease therapyMartine Aubert, Emily A Madden, Michelle Loprieno, et al.
Bioanalysis|June 21, 2018
Concerted application of LC-MS and ligand binding assays to better understand exposure of a large molecule drugWeifeng Xu, Hao Jiang, Craig Titsch, et al.
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