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Cell Reports|December 19, 2025
The RNA exosome maintains cellular RNA homeostasis by controlling transcript abundance in the brainLauryn A Higginson, Xingjun Wang, Kevin He, et al.Nature Communications|May 11, 2024
Effects of SPI1-mediated transcriptome remodeling on Alzheimer's disease-related phenotypes in mouse models of Aβ amyloidosisByungwook Kim, Luke Child Dabin, Mason Douglas Tate, et al.Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association|December 12, 2025
Deletion of neuronal Idol ameliorates Alzheimer's disease-related pathologies via APOE receptorsHande Karahan, Kelly Hartigan, Md Mamun Al-Amin, et al.Biorxiv : the Preprint Server for Biology|June 12, 2025
EXOSC3 S1-domain variants implicated in PCH1b alter RNA exosome cap subunit abundance and thermal stability disrupting rRNA processing and targeting of AU-rich mRNAAvery M Runnebohm, H R Sagara Wijeratne, Monica P Barron, et al.Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association|September 30, 2024
Deletion of miR-33, a regulator of the ABCA1-APOE pathway, ameliorates neuropathological phenotypes in APP/PS1 miceMason Tate, H R Sagara Wijeratne, Byungwook Kim, et al.Science Advances|November 3, 2021
Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer's disease in a mouse model of Aβ amyloidosisHande Karahan, Daniel C Smith, Byungwook Kim, et al.Neuron|April 3, 2026
Deletion of SPI1 in microglia exacerbates amyloid pathology by impairing microglial response in Alzheimer's disease modelsByungwook Kim, Mason Douglas Tate, Hande Karahan, et al.Biorxiv : the Preprint Server for Biology|February 9, 2026
EXOSC3 G191 Variants Trigger System-Wide Recalibration of RNA Processing MachineryH R Sagara Wijeratne, Avery M Runnebohm, Monica P Barron, et al.Biorxiv : the Preprint Server for Biology|February 13, 2023
Network analysis reveals strain-dependent response to misfolded tau aggregatesDominic J Acri, Yanwen You, Mason D Tate, et al.Science (New York, N.Y.)|July 29, 2017
Control of species-dependent cortico-motoneuronal connections underlying manual dexterityZirong Gu, John Kalambogias, Shin Yoshioka, et al.Pageof 3