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Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|June 4, 2008
Activity of the Bcl-2 family inhibitor ABT-263 in a panel of small cell lung cancer xenograft modelsAlex R Shoemaker, Michael J Mitten, Jessica Adickes, et al.Bioorganic & Medicinal Chemistry Letters|March 30, 2007
Discovery of a novel small molecule binding site of human survivinMichael D Wendt, Chaohong Sun, Aaron Kunzer, et al.Nature Medicine|March 21, 2026
Real-world clinical utility of tumor whole-genome sequencing in solid cancersJeffrey van Putten, Petur Snaebjornsson, Linda J W Bosch, et al.Bioorganic & Medicinal Chemistry Letters|September 28, 2010
Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMRAndrew M Petros, Jeffrey R Huth, Thorsten Oost, et al.Cancer Research|May 3, 2008
ABT-263: a potent and orally bioavailable Bcl-2 family inhibitorChristin Tse, Alexander R Shoemaker, Jessica Adickes, et al.Cell Death and Differentiation|January 6, 2007
Bcl-2 family proteins are essential for platelet survivalH Zhang, P M Nimmer, S K Tahir, et al.Journal of Medicinal Chemistry|October 22, 2009
Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as potent, highly selective, and orally bioavailable inhibitors of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM) kinasesZhi-Fu Tao, Lisa A Hasvold, Joel D Leverson, et al.Journal of Medicinal Chemistry|October 10, 2008
Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteinsCheol-Min Park, Milan Bruncko, Jessica Adickes, et al.Bioorganic & Medicinal Chemistry Letters|April 29, 2006
Discovery and SAR of oxindole-pyridine-based protein kinase B/Akt inhibitors for treating cancersGui-Dong Zhu, Viraj B Gandhi, Jianchun Gong, et al.Journal of Medicinal Chemistry|August 20, 2004
Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancerThorsten K Oost, Chaohong Sun, Robert C Armstrong, et al.Pageof 94