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Bioorganic & Medicinal Chemistry|July 18, 2006
Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitorsKeith W Woods, John P Fischer, Akiyo Claiborne, et al.Journal of Medicinal Chemistry|September 10, 1999
Second-generation peptidomimetic inhibitors of protein farnesyltransferase demonstrating improved cellular potency and significant in vivo efficacyS J O'Connor, K J Barr, L Wang, et al.Anticancer Research|November 28, 2008
The PARP inhibitor, ABT-888 potentiates temozolomide: correlation with drug levels and reduction in PARP activity in vivoJoann P Palma, Luis E Rodriguez, Velitchka D Bontcheva-Diaz, et al.Genetics in Medicine : Official Journal of the American College of Medical Genetics|November 25, 2023
Impact of genetic counseling strategy on diagnostic yield and workload for genome-sequencing-based tumor diagnosticsRoelof Koster, Luuk J Schipper, Noor A A Giesbertz, et al.Bioorganic & Medicinal Chemistry|June 11, 2008
Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancerThomas D Penning, Gui-Dong Zhu, Viraj B Gandhi, et al.Cancer Research|April 19, 2017
Preclinical Characterization of BET Family Bromodomain Inhibitor ABBV-075 Suggests Combination Therapeutic StrategiesMai H Bui, Xiaoyu Lin, Daniel H Albert, et al.Cancer Research|September 5, 2006
A small-molecule inhibitor of Bcl-XL potentiates the activity of cytotoxic drugs in vitro and in vivoAlex R Shoemaker, Anatol Oleksijew, Joy Bauch, et al.Journal of Medicinal Chemistry|December 1, 2001
New antimitotic agents with activity in multi-drug-resistant cell lines and in vivo efficacy in murine tumor modelsB G Szczepankiewicz, G Liu, H S Jae, et al.Journal of Medicinal Chemistry|May 26, 2007
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase B/Akt inhibitors with reduced hypotensionGui-Dong Zhu, Viraj B Gandhi, Jianchun Gong, et al.Anti-Cancer Drugs|October 14, 2005
A highly potent and selective farnesyltransferase inhibitor ABT-100 in preclinical studiesWen-Zhen Gu, Ingrid Joseph, Yi-Chun Wang, et al.Pageof 94