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Pharmaceutical Research|April 1, 1996
Evidence for intestinal secretion as an additional clearance pathway of talinolol enantiomers: concentration- and dose-dependent absorption in vitro and in vivoU Wetterich, H Spahn-Langguth, E Mutschler, et al.
Biopharmaceutics & Drug Disposition|January 1, 1983
Influence of inflammatory disease on the clinical pharmacokinetics of atenolol and metoprololW Kirch, H Spahn, E E Ohnhaus, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 1, 1997
Elucidation of phase I and phase II metabolic pathways of rhein: species differences and their potential relevanceM Dahms, R Lotz, W Lang, et al.
British Journal of Clinical Pharmacology|October 1, 1993
The pharmacokinetics of tranylcypromine enantiomers in healthy subjects after oral administration of racemic drug and the single enantiomersH Weber-Grandke, G Hahn, E Mutschler, et al.
Clinical Cardiology|February 1, 1987
Influence of cardiac function on the diuretic and hemodynamic effects of the loop diuretic piretanideG Hasenfuss, C Holubarsch, C Herzog, et al.
Clinical Pharmacology and Therapeutics|January 1, 1994
Enhanced covalent binding of tolmetin to proteins in humans after multiple dosingP Zia-Amirhosseini, J C Ojingwa, H Spahn-Langguth, et al.
The Journal of Pharmacology and Experimental Therapeutics|December 23, 1998
Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assayS Döppenschmitt, P Langguth, C G Regårdh, et al.
Journal of Pharmaceutical Sciences|February 9, 2000
Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transportC Hilgendorf, H Spahn-Langguth, C G Regårdh, et al.
International Journal of Clinical Pharmacology and Therapeutics|April 28, 2000
Affinities at the verapamil binding site of MDR1-encoded P-glycoprotein: drugs and analogs, stereoisomers and metabolitesS Neuhoff, P Langguth, C Dressler, et al.
Journal of Pharmacokinetics and Biopharmaceutics|June 1, 1995
Celiprolol double-peak occurrence and gastric motility: nonlinear mixed effects modeling of bioavailability data obtained in dogsE Lipka, I D Lee, P Langguth, et al.
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