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Therapeutic Immunology|February 1, 1995
A single-chain TNF receptor antagonist is an effective inhibitor of TNF mediated cytotoxicityD Moosmayer, S Dübel, B Brocks, et al.Cell Death and Differentiation|August 19, 2007
Enforced covalent trimerization increases the activity of the TNF ligand family members TRAIL and CD95LD Berg, M Lehne, N Müller, et al.European Journal of Immunology|June 26, 1999
TWEAK can induce cell death via endogenous TNF and TNF receptor 1P Schneider, R Schwenzer, E Haas, et al.The Journal of Biological Chemistry|June 26, 1999
The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinaseR Schwenzer, K Siemienski, S Liptay, et al.Journal of Immunology (Baltimore, Md. : 1950)|August 1, 1988
High affinity human IFN-gamma-binding capacity is encoded by a single receptor gene located in proximity to c-ros on human chromosome region 6q16 to 6q22K Pfizenmaier, K Wiegmann, P Scheurich, et al.Cell Death & Disease|March 3, 2011
Potent antitumoral activity of TRAIL through generation of tumor-targeted single-chain fusion proteinsB Schneider, S Münkel, A Krippner-Heidenreich, et al.The Journal of Biological Chemistry|May 24, 2000
Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)H Wajant, E Haas, R Schwenzer, et al.Current Biology : CB|March 21, 1998
Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene inductionH Wajant, F J Johannes, E Haas, et al.Cell Death and Differentiation|July 30, 2005
Restoration of membrane TNF-like activity by cell surface targeting and matrix metalloproteinase-mediated processing of a TNF prodrugJ Gerspach, D Müller, S Münkel, et al.The Journal of Biological Chemistry|June 1, 2001
Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathwayD Siegmund, D Mauri, N Peters, et al.Pageof 21