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ACS Medicinal Chemistry Letters|September 18, 2020
Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P1) Modulators: Optimization of the PK, PD, and Safety ProfilesZili Xiao, Michael G Yang, T G Murali Dhar, et al.Acta Pharmacologica Sinica|June 11, 2026
METTL3 loss exacerbates colitis via m6A-dependent Slc39a8 regulation and epithelial lineage depletionHao Su, De-Hua Liu, Hai-Yun Shang, et al.Cell|November 23, 2024
Atlas of the plasma proteome in health and disease in 53,026 adultsYue-Ting Deng, Jia You, Yu He, et al.Journal of Medicinal Chemistry|January 25, 2021
Bicyclic Ligand-Biased Agonists of S1P1: Exploring Side Chain Modifications to Modulate the PK, PD, and Safety ProfilesJohn L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.Redox Biology|September 1, 2020
Angiogenic and Antiangiogenic mechanisms of high density lipoprotein from healthy subjects and coronary artery diseases patientsHua-Ming Li, Zhi-Wei Mo, Yue-Ming Peng, et al.Journal of Medicinal Chemistry|March 19, 2004
N-(cycloalkylamino)acyl-2-aminothiazole inhibitors of cyclin-dependent kinase 2. N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a highly efficacious and selective antitumor agentRaj N Misra, Hai-yun Xiao, Kyoung S Kim, et al.Journal of Medicinal Chemistry|August 23, 2002
Discovery of aminothiazole inhibitors of cyclin-dependent kinase 2: synthesis, X-ray crystallographic analysis, and biological activitiesKyoung Soon Kim, S David Kimball, Raj N Misra, et al.ACS Medicinal Chemistry Letters|March 18, 2016
Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P1 Receptor Modulator in Clinical TrialsT G Murali Dhar, Hai-Yun Xiao, Jenny Xie, et al.Medchemcomm|August 16, 2018
Identification of potent tricyclic prodrug S1P1 receptor modulatorsDavid Marcoux, Hai-Yun Xiao, T G Murali Dhar, et al.Journal of Medicinal Chemistry|December 2, 2020
Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design ApproachesHai-Yun Xiao, Ning Li, James J-W Duan, et al.Pageof 64