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Haifeng Tang

Showing results (121-130 of 131) with videos related to

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Bioorganic & Medicinal Chemistry Letters|March 28, 2016
Differentiation of ROMK potency from hERG potency in the phenacetyl piperazine series through heterocycle incorporationShawn P Walsh, Aurash Shahripour, Haifeng Tang, et al.
Journal of Medicinal Chemistry|May 26, 2021
Discovery of MK-8153, a Potent and Selective ROMK Inhibitor and Novel Diuretic/NatriureticJinlong Jiang, Fa-Xiang Ding, Xiaoyan Zhou, et al.
ACS Medicinal Chemistry Letters|July 21, 2016
Discovery of MK-7145, an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart FailureHaifeng Tang, Yuping Zhu, Nardos Teumelsan, et al.
Bioorganic & Medicinal Chemistry Letters|April 23, 2017
Improvement of hERG-ROMK index of spirocyclic ROMK inhibitors through scaffold optimization and incorporation of novel pharmacophoresShuzhi Dong, Kelsey VanGelder, Zhi-Cai Shi, et al.
Nature|September 30, 2015
Selective small-molecule inhibition of an RNA structural elementJohn A Howe, Hao Wang, Thierry O Fischmann, et al.
Bioorganic & Medicinal Chemistry Letters|November 15, 2016
Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino[2,1-c][1,4]oxazine scaffoldYuping Zhu, Reynalda K de Jesus, Haifeng Tang, et al.
Journal of Medicinal Chemistry|March 22, 2017
Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO InhibitorMihirbaran Mandal, Zheng Tan, Christina Madsen-Duggan, et al.
ACS Medicinal Chemistry Letters|July 21, 2015
Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical EvaluationShawn P Walsh, Aurash Shahripour, Haifeng Tang, et al.
Journal of Medicinal Chemistry|April 28, 2022
Discovery of a Novel Class of d-Amino Acid Oxidase Inhibitors Using the Schrödinger Computational PlatformHaifeng Tang, Kristian Jensen, Evelyne Houang, et al.
Journal of Medicinal Chemistry|December 8, 2022
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical CandidatesMihirbaran Mandal, Li Xiao, Weidong Pan, et al.
Pageof 14

Showing results (121-130 of 131) with videos related to

Sort By:
Pageof 14
Bioorganic & Medicinal Chemistry Letters|March 28, 2016
Differentiation of ROMK potency from hERG potency in the phenacetyl piperazine series through heterocycle incorporationShawn P Walsh, Aurash Shahripour, Haifeng Tang, et al.
Journal of Medicinal Chemistry|May 26, 2021
Discovery of MK-8153, a Potent and Selective ROMK Inhibitor and Novel Diuretic/NatriureticJinlong Jiang, Fa-Xiang Ding, Xiaoyan Zhou, et al.
ACS Medicinal Chemistry Letters|July 21, 2016
Discovery of MK-7145, an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart FailureHaifeng Tang, Yuping Zhu, Nardos Teumelsan, et al.
Bioorganic & Medicinal Chemistry Letters|April 23, 2017
Improvement of hERG-ROMK index of spirocyclic ROMK inhibitors through scaffold optimization and incorporation of novel pharmacophoresShuzhi Dong, Kelsey VanGelder, Zhi-Cai Shi, et al.
Nature|September 30, 2015
Selective small-molecule inhibition of an RNA structural elementJohn A Howe, Hao Wang, Thierry O Fischmann, et al.
Bioorganic & Medicinal Chemistry Letters|November 15, 2016
Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino[2,1-c][1,4]oxazine scaffoldYuping Zhu, Reynalda K de Jesus, Haifeng Tang, et al.
Journal of Medicinal Chemistry|March 22, 2017
Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO InhibitorMihirbaran Mandal, Zheng Tan, Christina Madsen-Duggan, et al.
ACS Medicinal Chemistry Letters|July 21, 2015
Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical EvaluationShawn P Walsh, Aurash Shahripour, Haifeng Tang, et al.
Journal of Medicinal Chemistry|April 28, 2022
Discovery of a Novel Class of d-Amino Acid Oxidase Inhibitors Using the Schrödinger Computational PlatformHaifeng Tang, Kristian Jensen, Evelyne Houang, et al.
Journal of Medicinal Chemistry|December 8, 2022
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical CandidatesMihirbaran Mandal, Li Xiao, Weidong Pan, et al.
Pageof 14