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The Journal of Pharmacology and Experimental Therapeutics|October 22, 2002
Cholestasis increases tumor necrosis factor-related apoptotis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicityHajime Higuchi, Steven F Bronk, Makiko Taniai, et al.
The Journal of Biological Chemistry|October 17, 2003
Bile acids up-regulate death receptor 5/TRAIL-receptor 2 expression via a c-Jun N-terminal kinase-dependent pathway involving Sp1Hajime Higuchi, Annette Grambihler, Ali Canbay, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology|May 15, 2003
Apoptotic body engulfment by a human stellate cell line is profibrogenicAli Canbay, Pavel Taimr, Natalie Torok, et al.
Gastroenterology|March 23, 2002
Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell lineJung-Hwan Yoon, Hajime Higuchi, Nathan W Werneburg, et al.
Hepatology (Baltimore, Md.)|December 25, 2002
Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosisPavel Taimr, Hajime Higuchi, Eva Kocova, et al.
Gastroenterology|October 3, 2002
Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosisAli Canbay, Hajime Higuchi, Steven F Bronk, et al.
The Journal of Biological Chemistry|October 31, 2002
Bile acids stimulate cFLIP phosphorylation enhancing TRAIL-mediated apoptosisHajime Higuchi, Jung-Hwan Yoon, Annette Grambihler, et al.
American Journal of Physiology. Gastrointestinal and Liver Physiology|March 27, 2004
Bax interacts with the voltage-dependent anion channel and mediates ethanol-induced apoptosis in rat hepatocytesMasayuki Adachi, Hajime Higuchi, Soichiro Miura, et al.
Journal of Hepatology|December 4, 2003
Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in miceAriel E Feldstein, Ali Canbay, Maria E Guicciardi, et al.
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