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Hakan Gunaydin

Showing results (21-30 of 45) with videos related to

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Bioorganic & Medicinal Chemistry Letters|August 11, 2012
2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1γ) inhibitorsZihao Hua, Xin Huang, Howard Bregman, et al.
ACS Medicinal Chemistry Letters|January 19, 2019
Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STINGTony Siu, Michael D Altman, Gretchen A Baltus, et al.
Bioorganic & Medicinal Chemistry Letters|March 2, 2016
Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitorsVladimir Simov, Sujal V Deshmukh, Christopher J Dinsmore, et al.
The Journal of Organic Chemistry|March 31, 2012
Synthesis of 4-substituted chlorophthalazines, dihydrobenzoazepinediones, 2-pyrazolylbenzoic acid, and 2-pyrazolylbenzohydrazide via 3-substituted 3-hydroxyisoindolin-1-onesHanh Nho Nguyen, Victor J Cee, Holly L Deak, et al.
Journal of Medicinal Chemistry|April 19, 2017
Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity ProfilesJohn M Sanders, Douglas C Beshore, J Christopher Culberson, et al.
Journal of Medicinal Chemistry|March 5, 2016
Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo ActivityLaurie B Schenkel, Philip R Olivieri, Alessandro A Boezio, et al.
Journal of Medicinal Chemistry|May 25, 2013
Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitorsHoward Bregman, Nagasree Chakka, Angel Guzman-Perez, et al.
Journal of Medicinal Chemistry|November 18, 2011
Discovery of potent and highly selective thienopyridine Janus kinase 2 inhibitorsLaurie B Schenkel, Xin Huang, Alan Cheng, et al.
Bioorganic & Medicinal Chemistry Letters|May 1, 2018
1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of Na<sub>V</sub>1.7 inhibitionAlessandro A Boezio, Kristin Andrews, Christiane Boezio, et al.
Journal of Medicinal Chemistry|December 22, 2016
The Discovery and Hit-to-Lead Optimization of Tricyclic Sulfonamides as Potent and Efficacious Potentiators of Glycine ReceptorsHoward Bregman, Jeffrey R Simard, Kristin L Andrews, et al.
Pageof 5

Showing results (21-30 of 45) with videos related to

Sort By:
Pageof 5
Bioorganic & Medicinal Chemistry Letters|August 11, 2012
2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1γ) inhibitorsZihao Hua, Xin Huang, Howard Bregman, et al.
ACS Medicinal Chemistry Letters|January 19, 2019
Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STINGTony Siu, Michael D Altman, Gretchen A Baltus, et al.
Bioorganic & Medicinal Chemistry Letters|March 2, 2016
Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitorsVladimir Simov, Sujal V Deshmukh, Christopher J Dinsmore, et al.
The Journal of Organic Chemistry|March 31, 2012
Synthesis of 4-substituted chlorophthalazines, dihydrobenzoazepinediones, 2-pyrazolylbenzoic acid, and 2-pyrazolylbenzohydrazide via 3-substituted 3-hydroxyisoindolin-1-onesHanh Nho Nguyen, Victor J Cee, Holly L Deak, et al.
Journal of Medicinal Chemistry|April 19, 2017
Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity ProfilesJohn M Sanders, Douglas C Beshore, J Christopher Culberson, et al.
Journal of Medicinal Chemistry|March 5, 2016
Optimization of a Novel Quinazolinone-Based Series of Transient Receptor Potential A1 (TRPA1) Antagonists Demonstrating Potent in Vivo ActivityLaurie B Schenkel, Philip R Olivieri, Alessandro A Boezio, et al.
Journal of Medicinal Chemistry|May 25, 2013
Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitorsHoward Bregman, Nagasree Chakka, Angel Guzman-Perez, et al.
Journal of Medicinal Chemistry|November 18, 2011
Discovery of potent and highly selective thienopyridine Janus kinase 2 inhibitorsLaurie B Schenkel, Xin Huang, Alan Cheng, et al.
Bioorganic & Medicinal Chemistry Letters|May 1, 2018
1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of Na<sub>V</sub>1.7 inhibitionAlessandro A Boezio, Kristin Andrews, Christiane Boezio, et al.
Journal of Medicinal Chemistry|December 22, 2016
The Discovery and Hit-to-Lead Optimization of Tricyclic Sulfonamides as Potent and Efficacious Potentiators of Glycine ReceptorsHoward Bregman, Jeffrey R Simard, Kristin L Andrews, et al.
Pageof 5