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Proceedings of the National Academy of Sciences of the United States of America|November 2, 2016
GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammationSudipta Das, Marina Miller, Andrew K Beppu, et al.Journal of Medical Genetics|March 31, 2018
New workflow for classification of genetic variants' pathogenicity applied to hereditary recurrent fevers by the International Study Group for Systemic Autoinflammatory Diseases (INSAID)Marielle E Van Gijn, Isabella Ceccherini, Yael Shinar, et al.Nature Communications|July 21, 2019
Alternative splicing regulates stochastic NLRP3 activityFlorian Hoss, James L Mueller, Francisca Rojas Ringeling, et al.JCI Insight|January 31, 2020
ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury modelSusanne Schuster-Gaul, Lukas Jonathan Geisler, Matthew D McGeough, et al.Communications Biology|April 16, 2026
TH5487 specifically targets NLRP3 in FCAS patients resistant to MCC950Angela Lackner, Sofia I Picucci, Wenjin Jiang, et al.Journal of Clinical Immunology|August 29, 2012
Mutations of complement factor I and potential mechanisms of neuroinflammation in acute hemorrhagic leukoencephalitisLori Broderick, Chhavi Gandhi, James L Mueller, et al.Cell Metabolism|April 16, 2019
Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 ProductionElsa Sanchez-Lopez, Zhenyu Zhong, Alexandra Stubelius, et al.Arteriosclerosis, Thrombosis, and Vascular Biology|March 5, 2016
Role of Interleukin-1 Signaling in a Mouse Model of Kawasaki Disease-Associated Abdominal Aortic AneurysmDaiko Wakita, Yosuke Kurashima, Timothy R Crother, et al.The Journal of Pharmacology and Experimental Therapeutics|June 12, 2023
Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver FibrosisDavide Povero, Milos Lazic, Christopher McBride, et al.Journal of Leukocyte Biology|April 4, 2007
MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3Qilin Pan, John Mathison, Colleen Fearns, et al.Pageof 20