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ACS Medicinal Chemistry Letters|June 6, 2014
Imidazopyridine-Based Fatty Acid Synthase Inhibitors That Show Anti-HCV Activity and in Vivo Target ModulationJohan D Oslob, Russell J Johnson, Haiying Cai, et al.Journal of the American Chemical Society|April 6, 2006
Surface-rolling moleculesYasuhiro Shirai, Andrew J Osgood, Yuming Zhao, et al.Bioorganic & Medicinal Chemistry Letters|June 30, 2010
Cyclic amide bioisosterism: strategic application to the design and synthesis of HCV NS5B polymerase inhibitorsHanbiao Yang, Robert T Hendricks, Nidhi Arora, et al.Journal of Medicinal Chemistry|July 9, 2019
3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell CarcinomaRui Xu, Keshi Wang, James P Rizzi, et al.Cancer Research|September 17, 2016
A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell CarcinomaEli M Wallace, James P Rizzi, Guangzhou Han, et al.Journal of Medicinal Chemistry|October 6, 2018
Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate ( S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1 H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385)Paul M Wehn, James P Rizzi, Darryl D Dixon, et al.Pageof 2