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Assay and Drug Development Technologies
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April 15, 2016
Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening
Karin Engen, Ulrika Rosenström, Hanna Axelsson, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
July 14, 2017
Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery
André Mateus, Laurie J Gordon, Gareth J Wayne, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|
June 1, 2026
Standardized workflow enables reproducibility of drug synergism detection: Results from a multi-center in vitro ring test on complex drug combinations in pancreatic cancer models
Veronica Barile, Maria Kuzikov, Weiyingqi Cui, et al.
Journal of Biomolecular Screening
|
May 31, 2012
A homogeneous HTRF assay for the identification of inhibitors of the TWEAK-Fn14 protein interaction
Tiziana Benicchi, Sara Iozzi, Andreas Svahn, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|
August 17, 2025
Image based subcellular mapping of the protein landscape of SARS-CoV-2 infected cells for target-centric drug repurposing
Marianna Tampere, Trang H Le, Elin Asp, et al.
Nature Communications
|
January 19, 2018
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Brent D G Page, Nicholas C K Valerie, Roni H G Wright, et al.
Nature Communications
|
November 3, 2019
Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Brent D G Page, Nicholas C K Valerie, Roni H G Wright, et al.
Iscience
|
February 6, 2024
Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel
Si Min Zhang, Cynthia B J Paulin, Huazhang Shu, et al.
EMBO Molecular Medicine
|
January 18, 2020
Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy
Sean G Rudd, Nikolaos Tsesmetzis, Kumar Sanjiv, et al.
Nature Medicine
|
January 10, 2017
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
Nikolas Herold, Sean G Rudd, Linda Ljungblad, et al.
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Search research articles
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Showing results (11-20 of 22) with videos related to
Sort By:
Page
of 3
Assay and Drug Development Technologies
|
April 15, 2016
Identification of Drug-Like Inhibitors of Insulin-Regulated Aminopeptidase Through Small-Molecule Screening
Karin Engen, Ulrika Rosenström, Hanna Axelsson, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
July 14, 2017
Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery
André Mateus, Laurie J Gordon, Gareth J Wayne, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|
June 1, 2026
Standardized workflow enables reproducibility of drug synergism detection: Results from a multi-center in vitro ring test on complex drug combinations in pancreatic cancer models
Veronica Barile, Maria Kuzikov, Weiyingqi Cui, et al.
Journal of Biomolecular Screening
|
May 31, 2012
A homogeneous HTRF assay for the identification of inhibitors of the TWEAK-Fn14 protein interaction
Tiziana Benicchi, Sara Iozzi, Andreas Svahn, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|
August 17, 2025
Image based subcellular mapping of the protein landscape of SARS-CoV-2 infected cells for target-centric drug repurposing
Marianna Tampere, Trang H Le, Elin Asp, et al.
Nature Communications
|
January 19, 2018
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Brent D G Page, Nicholas C K Valerie, Roni H G Wright, et al.
Nature Communications
|
November 3, 2019
Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Brent D G Page, Nicholas C K Valerie, Roni H G Wright, et al.
Iscience
|
February 6, 2024
Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel
Si Min Zhang, Cynthia B J Paulin, Huazhang Shu, et al.
EMBO Molecular Medicine
|
January 18, 2020
Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy
Sean G Rudd, Nikolaos Tsesmetzis, Kumar Sanjiv, et al.
Nature Medicine
|
January 10, 2017
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
Nikolas Herold, Sean G Rudd, Linda Ljungblad, et al.
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of 3