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Medizinische Genetik : Mitteilungsblatt Des Berufsverbandes Medizinische Genetik E.V|July 8, 2026
An introduction to polygenic scores - methodological basics and recent advancesHannah Klinkhammer, Andreas Mayr, Carlo Maj
BMC Medical Genomics|May 16, 2024
Generalizability of polygenic prediction models: how is the R2 defined on test data?Christian Staerk, Hannah Klinkhammer, Tobias Wistuba, et al.
Frontiers in Genetics|January 27, 2023
A statistical boosting framework for polygenic risk scores based on large-scale genotype dataHannah Klinkhammer, Christian Staerk, Carlo Maj, et al.
Statistics in Medicine|October 23, 2024
Genetic Prediction Modeling in Large Cohort Studies via Boosting Targeted Loss FunctionsHannah Klinkhammer, Christian Staerk, Carlo Maj, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 1, 2026
Detecting gene-environment interactions to guide personalized intervention: Boosting distributional regression for polygenic scoresQiong Wu, Hannah Klinkhammer, Kiran Kunwar, et al.
Frontiers in Bioinformatics|June 29, 2026
Polygenic modeling of genetic effects on both phenotypic mean and variance: distributional regression for BMI, blood and urine biomarkers in the UK BiobankKiran Kunwar, Qiong Wu, Hannah Klinkhammer, et al.
Genetic Epidemiology|August 8, 2022
Statistical learning for sparser fine-mapped polygenic models: The prediction of LDL-cholesterolCarlo Maj, Christian Staerk, Oleg Borisov, et al.
HGG Advances|March 28, 2026
Investigations on transferability of polygenic risk scores depending on demography and dominance coefficientsLeonie Fohler, Edita Latifi, Andreas Mayr, et al.
Bioinformatics (Oxford, England)|March 10, 2022
GenRisk: a tool for comprehensive genetic risk modelingRana Aldisi, Emadeldin Hassanin, Sugirthan Sivalingam, et al.
BMC Genomic Data|September 4, 2023
Gene-based burden scores identify rare variant associations for 28 blood biomarkersRana Aldisi, Emadeldin Hassanin, Sugirthan Sivalingam, et al.
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