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Hans Briem

Showing results (11-20 of 31) with videos related to

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Journal of Chemical Information and Modeling|May 24, 2014
Facing the challenges of structure-based target prediction by inverse virtual screeningKaren T Schomburg, Stefan Bietz, Hans Briem, et al.
Chemmedchem|November 30, 2006
Macrocyclic aminopyrimidines as multitarget CDK and VEGF-R inhibitors with potent antiproliferative activitiesUlrich Lücking, Gerhard Siemeister, Martina Schäfer, et al.
Drug Discovery Today|December 19, 2018
An approach towards enhancement of a screening library: The Next Generation Library Initiative (NGLI) at Bayer - against all odds?Markus Follmann, Hans Briem, Andreas Steinmeyer, et al.
Chembiochem : a European Journal of Chemical Biology|March 3, 2005
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitorsRolf Jautelat, Thomas Brumby, Martina Schäfer, et al.
Acta Crystallographica. Section D, Biological Crystallography|March 2, 2011
A crystallographic fragment screen identifies cinnamic acid derivatives as starting points for potent Pim-1 inhibitorsMichèle N Schulz, Jörg Fanghänel, Martina Schäfer, et al.
European Journal of Nuclear Medicine and Molecular Imaging|October 26, 2023
Mono- and multimeric PSMA-targeting small molecule-thorium-227 conjugates for optimized efficacy and biodistribution in preclinical modelsNiels Böhnke, Bård Indrevoll, Stefanie Hammer, et al.
Chemmedchem|October 14, 2022
Prioritizing Small Sets of Molecules for Synthesis through in-silico Tools: A Comparison of Common Ranking MethodsMarko Breznik, Yunhui Ge, Joseph P Bluck, et al.
Journal of Computer-Aided Molecular Design|December 29, 2011
Substantial improvements in large-scale redocking and screening using the novel HYDE scoring functionNadine Schneider, Sally Hindle, Gudrun Lange, et al.
Chemmedchem|May 15, 2013
The lab oddity prevails: discovery of pan-CDK inhibitor (R)-S-cyclopropyl-S-(4-{[4-{[(1R,2R)-2-hydroxy-1-methylpropyl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)sulfoximide (BAY 1000394) for the treatment of cancerUlrich Lücking, Rolf Jautelat, Martin Krüger, et al.
Chemmedchem|April 3, 2020
Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRAS<sup>G12C</sup>Jérémie Mortier, Anders Friberg, Volker Badock, et al.
Pageof 4

Showing results (11-20 of 31) with videos related to

Sort By:
Pageof 4
Journal of Chemical Information and Modeling|May 24, 2014
Facing the challenges of structure-based target prediction by inverse virtual screeningKaren T Schomburg, Stefan Bietz, Hans Briem, et al.
Chemmedchem|November 30, 2006
Macrocyclic aminopyrimidines as multitarget CDK and VEGF-R inhibitors with potent antiproliferative activitiesUlrich Lücking, Gerhard Siemeister, Martina Schäfer, et al.
Drug Discovery Today|December 19, 2018
An approach towards enhancement of a screening library: The Next Generation Library Initiative (NGLI) at Bayer - against all odds?Markus Follmann, Hans Briem, Andreas Steinmeyer, et al.
Chembiochem : a European Journal of Chemical Biology|March 3, 2005
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitorsRolf Jautelat, Thomas Brumby, Martina Schäfer, et al.
Acta Crystallographica. Section D, Biological Crystallography|March 2, 2011
A crystallographic fragment screen identifies cinnamic acid derivatives as starting points for potent Pim-1 inhibitorsMichèle N Schulz, Jörg Fanghänel, Martina Schäfer, et al.
European Journal of Nuclear Medicine and Molecular Imaging|October 26, 2023
Mono- and multimeric PSMA-targeting small molecule-thorium-227 conjugates for optimized efficacy and biodistribution in preclinical modelsNiels Böhnke, Bård Indrevoll, Stefanie Hammer, et al.
Chemmedchem|October 14, 2022
Prioritizing Small Sets of Molecules for Synthesis through in-silico Tools: A Comparison of Common Ranking MethodsMarko Breznik, Yunhui Ge, Joseph P Bluck, et al.
Journal of Computer-Aided Molecular Design|December 29, 2011
Substantial improvements in large-scale redocking and screening using the novel HYDE scoring functionNadine Schneider, Sally Hindle, Gudrun Lange, et al.
Chemmedchem|May 15, 2013
The lab oddity prevails: discovery of pan-CDK inhibitor (R)-S-cyclopropyl-S-(4-{[4-{[(1R,2R)-2-hydroxy-1-methylpropyl]oxy}-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)sulfoximide (BAY 1000394) for the treatment of cancerUlrich Lücking, Rolf Jautelat, Martin Krüger, et al.
Chemmedchem|April 3, 2020
Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRAS<sup>G12C</sup>Jérémie Mortier, Anders Friberg, Volker Badock, et al.
Pageof 4