Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Filters

Hans Gaus

Showing results (11-20 of 34) with videos related to

Pageof 4
Sort By:
The Journal of Organic Chemistry|November 10, 2005
Formation of modified cytosine residues in the presence of depurinated DNAClaus Rentel, Xiaojing Wang, Michael Batt, et al.
Bioorganic & Medicinal Chemistry Letters|November 9, 2005
Characterization of high molecular weight impurities in synthetic phosphorothioate oligonucleotidesChristine Kurata, Kym Bradley, Hans Gaus, et al.
ACS Medicinal Chemistry Letters|June 18, 2021
Site-specific Incorporation of 2',5'-Linked Nucleic Acids Enhances Therapeutic Profile of Antisense OligonucleotidesThazha P Prakash, Jinghua Yu, Wen Shen, et al.
Journal of Medicinal Chemistry|November 10, 2010
Configuration of the 5'-methyl group modulates the biophysical and biological properties of locked nucleic acid (LNA) oligonucleotidesPunit P Seth, Charles R Allerson, Andrew Siwkowski, et al.
Journal of the American Chemical Society|October 5, 2010
An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNAPunit P Seth, Charles R Allerson, Andres Berdeja, et al.
The Journal of Organic Chemistry|February 9, 2010
Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analoguesPunit P Seth, Guillermo Vasquez, Charles A Allerson, et al.
The Journal of Organic Chemistry|March 1, 2023
Systematic Investigation of Tether Length and Phosphorus Configuration in Backbone Constrained Macrocyclic Nucleic Acids to Modulate Binding Kinetics for RNATamilselvan Rajasekaran, Graeme C Freestone, Rodrigo Galindo-Murillo, et al.
Nucleic Acids Symposium Series (2004)|September 9, 2008
Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogsPunit P Seth, Andrew Siwkowski, Charles R Allerson, et al.
Bioorganic & Medicinal Chemistry Letters|June 9, 2016
Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytesGarth A Kinberger, Thazha P Prakash, Jinghua Yu, et al.
Journal of the American Chemical Society|September 17, 2011
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotidesMartin Egli, Pradeep S Pallan, Charles R Allerson, et al.
Pageof 4

Showing results (11-20 of 34) with videos related to

Sort By:
Pageof 4
The Journal of Organic Chemistry|November 10, 2005
Formation of modified cytosine residues in the presence of depurinated DNAClaus Rentel, Xiaojing Wang, Michael Batt, et al.
Bioorganic & Medicinal Chemistry Letters|November 9, 2005
Characterization of high molecular weight impurities in synthetic phosphorothioate oligonucleotidesChristine Kurata, Kym Bradley, Hans Gaus, et al.
ACS Medicinal Chemistry Letters|June 18, 2021
Site-specific Incorporation of 2',5'-Linked Nucleic Acids Enhances Therapeutic Profile of Antisense OligonucleotidesThazha P Prakash, Jinghua Yu, Wen Shen, et al.
Journal of Medicinal Chemistry|November 10, 2010
Configuration of the 5'-methyl group modulates the biophysical and biological properties of locked nucleic acid (LNA) oligonucleotidesPunit P Seth, Charles R Allerson, Andrew Siwkowski, et al.
Journal of the American Chemical Society|October 5, 2010
An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNAPunit P Seth, Charles R Allerson, Andres Berdeja, et al.
The Journal of Organic Chemistry|February 9, 2010
Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analoguesPunit P Seth, Guillermo Vasquez, Charles A Allerson, et al.
The Journal of Organic Chemistry|March 1, 2023
Systematic Investigation of Tether Length and Phosphorus Configuration in Backbone Constrained Macrocyclic Nucleic Acids to Modulate Binding Kinetics for RNATamilselvan Rajasekaran, Graeme C Freestone, Rodrigo Galindo-Murillo, et al.
Nucleic Acids Symposium Series (2004)|September 9, 2008
Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogsPunit P Seth, Andrew Siwkowski, Charles R Allerson, et al.
Bioorganic & Medicinal Chemistry Letters|June 9, 2016
Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytesGarth A Kinberger, Thazha P Prakash, Jinghua Yu, et al.
Journal of the American Chemical Society|September 17, 2011
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotidesMartin Egli, Pradeep S Pallan, Charles R Allerson, et al.
Pageof 4