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Hans Gaus

Showing results (21-30 of 33) with videos related to

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Nucleic Acids Research|March 11, 2015
Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activityThazha P Prakash, Walt F Lima, Heather M Murray, et al.
Bioorganic & Medicinal Chemistry Letters|August 25, 2015
Solid-phase synthesis of 5'-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistryThazha P Prakash, W Brad Wan, Audrey Low, et al.
Journal of the American Chemical Society|January 18, 2022
Backbone Hydrocarbon-Constrained Nucleic Acids Modulate Hybridization Kinetics for RNATamilselvan Rajasekaran, Graeme C Freestone, Rodrigo Galindo-Murillo, et al.
Arthritis and Rheumatism|April 1, 2009
Amphoteric liposomes enable systemic antigen-presenting cell-directed delivery of CD40 antisense and are therapeutically effective in experimental arthritisEvangelos Andreakos, Una Rauchhaus, Athanassios Stavropoulos, et al.
Nucleic Acids Research|November 16, 2014
Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkagesW Brad Wan, Michael T Migawa, Guillermo Vasquez, et al.
The Journal of Pharmacology and Experimental Therapeutics|May 3, 2014
Pharmacology of a central nervous system delivered 2'-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primatesFrank Rigo, Seung J Chun, Daniel A Norris, et al.
Cell|September 4, 2012
Single-stranded siRNAs activate RNAi in animalsWalt F Lima, Thazha P Prakash, Heather M Murray, et al.
Haematologica|February 11, 2021
Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregatesMartina H Lundberg Slingsby, Prakrith Vijey, I-Ting Tsai, et al.
Nucleic Acids Research|April 30, 2019
Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteinsMichael T Migawa, Wen Shen, W Brad Wan, et al.
Journal of Medicinal Chemistry|April 28, 2010
Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissueEdward V Wancewicz, Martin A Maier, Andrew M Siwkowski, et al.
Pageof 4

Showing results (21-30 of 33) with videos related to

Sort By:
Pageof 4
Nucleic Acids Research|March 11, 2015
Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activityThazha P Prakash, Walt F Lima, Heather M Murray, et al.
Bioorganic & Medicinal Chemistry Letters|August 25, 2015
Solid-phase synthesis of 5'-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistryThazha P Prakash, W Brad Wan, Audrey Low, et al.
Journal of the American Chemical Society|January 18, 2022
Backbone Hydrocarbon-Constrained Nucleic Acids Modulate Hybridization Kinetics for RNATamilselvan Rajasekaran, Graeme C Freestone, Rodrigo Galindo-Murillo, et al.
Arthritis and Rheumatism|April 1, 2009
Amphoteric liposomes enable systemic antigen-presenting cell-directed delivery of CD40 antisense and are therapeutically effective in experimental arthritisEvangelos Andreakos, Una Rauchhaus, Athanassios Stavropoulos, et al.
Nucleic Acids Research|November 16, 2014
Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkagesW Brad Wan, Michael T Migawa, Guillermo Vasquez, et al.
The Journal of Pharmacology and Experimental Therapeutics|May 3, 2014
Pharmacology of a central nervous system delivered 2'-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primatesFrank Rigo, Seung J Chun, Daniel A Norris, et al.
Cell|September 4, 2012
Single-stranded siRNAs activate RNAi in animalsWalt F Lima, Thazha P Prakash, Heather M Murray, et al.
Haematologica|February 11, 2021
Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregatesMartina H Lundberg Slingsby, Prakrith Vijey, I-Ting Tsai, et al.
Nucleic Acids Research|April 30, 2019
Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteinsMichael T Migawa, Wen Shen, W Brad Wan, et al.
Journal of Medicinal Chemistry|April 28, 2010
Peptide nucleic acids conjugated to short basic peptides show improved pharmacokinetics and antisense activity in adipose tissueEdward V Wancewicz, Martin A Maier, Andrew M Siwkowski, et al.
Pageof 4