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Nature Communications|August 10, 2021
An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organismJerod L Ptacin, Carolina E Caffaro, Lina Ma, et al.Cell Reports|December 12, 2019
Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose ProductionBrandon M Gassaway, Rebecca L Cardone, Anil K Padyana, et al.Journal of Immunology (Baltimore, Md. : 1950)|August 12, 2025
SAR-444245, an engineered not-alpha IL-2 leveraging synthetic biology, modulates critical components of the immune system for durable anti-tumoral activityLina Ma, Nicole V Acuff, Jerod L Ptacin, et al.Communications Medicine|March 27, 2024
A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organismJerod L Ptacin, Lina Ma, Carolina E Caffaro, et al.Cancer Research Communications|September 25, 2024
A Precision Engineered Interleukin-2 for Bolstering CD8+ T- and NK-cell Activity without Eosinophilia and Vascular Leak Syndrome in Nonhuman PrimatesLina Ma, Nicole V Acuff, Ingrid B Joseph, et al.Pageof 2