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Hans-Georg Lerchen

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Bioorganic & Medicinal Chemistry Letters|October 13, 2009
Arginine-pyrimidine conjugates with therapeutic and prophylactic activity in lethal bacterial infectionsDieter Haebich, Hein-Peter Kroll, Hans-Georg Lerchen
Beilstein Journal of Organic Chemistry|December 5, 2012
Synthetic studies towards bottromycinStefanie Ackermann, Hans-Georg Lerchen, Dieter Häbich, et al.
Oncoimmunology|February 14, 2022
Antibody-drug conjugates harboring a kinesin spindle protein inhibitor with immunostimulatory propertiesAnette Sommer, Sandra Berndt, Hans-Georg Lerchen, et al.
Frontiers in Pharmacology|March 18, 2024
Neutrophil elastase as a versatile cleavage enzyme for activation of αvβ3 integrin-targeted small molecule drug conjugates with different payload classes in the tumor microenvironmentAnne-Sophie Rebstock, Mareike Wiedmann, Beatrix Stelte-Ludwig, et al.
Bioconjugate Chemistry|July 16, 2020
Tailored Linker Chemistries for the Efficient and Selective Activation of ADCs with KSPi PayloadsHans-Georg Lerchen, Beatrix Stelte-Ludwig, Anette Sommer, et al.
Cancers|January 21, 2022
A Small Molecule-Drug Conjugate (SMDC) Consisting of a Modified Camptothecin Payload Linked to an α<sub>V</sub>ß<sub>3</sub> Binder for the Treatment of Multiple Cancer TypesHans-Georg Lerchen, Beatrix Stelte-Ludwig, Charlotte Kopitz, et al.
The Journal of Organic Chemistry|December 10, 2019
A Selective Carborane-Functionalized Gastrin-Releasing Peptide Receptor Agonist as Boron Delivery Agent for Boron Neutron Capture TherapyPaul Hoppenz, Sylvia Els-Heindl, Martin Kellert, et al.
Cancers|September 9, 2023
Discovery of VIP236, an αvβ3-Targeted Small-Molecule-Drug Conjugate with Neutrophil Elastase-Mediated Activation of 7-Ethyl Camptothecin Payload for Treatment of Solid TumorsHans-Georg Lerchen, Beatrix Stelte-Ludwig, Melanie Heroult, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|March 15, 2019
Antibody-Prodrug Conjugates with KSP Inhibitors and Legumain-Mediated Metabolite FormationHans-Georg Lerchen, Beatrix Stelte-Ludwig, Sandra Berndt, et al.
Angewandte Chemie (International Ed. in English)|September 5, 2018
Antibody-Drug Conjugates with Pyrrole-Based KSP Inhibitors as the Payload ClassHans-Georg Lerchen, Sven Wittrock, Beatrix Stelte-Ludwig, et al.
Pageof 2

Showing results (1-10 of 15) with videos related to

Sort By:
Pageof 2
Bioorganic & Medicinal Chemistry Letters|October 13, 2009
Arginine-pyrimidine conjugates with therapeutic and prophylactic activity in lethal bacterial infectionsDieter Haebich, Hein-Peter Kroll, Hans-Georg Lerchen
Beilstein Journal of Organic Chemistry|December 5, 2012
Synthetic studies towards bottromycinStefanie Ackermann, Hans-Georg Lerchen, Dieter Häbich, et al.
Oncoimmunology|February 14, 2022
Antibody-drug conjugates harboring a kinesin spindle protein inhibitor with immunostimulatory propertiesAnette Sommer, Sandra Berndt, Hans-Georg Lerchen, et al.
Frontiers in Pharmacology|March 18, 2024
Neutrophil elastase as a versatile cleavage enzyme for activation of αvβ3 integrin-targeted small molecule drug conjugates with different payload classes in the tumor microenvironmentAnne-Sophie Rebstock, Mareike Wiedmann, Beatrix Stelte-Ludwig, et al.
Bioconjugate Chemistry|July 16, 2020
Tailored Linker Chemistries for the Efficient and Selective Activation of ADCs with KSPi PayloadsHans-Georg Lerchen, Beatrix Stelte-Ludwig, Anette Sommer, et al.
Cancers|January 21, 2022
A Small Molecule-Drug Conjugate (SMDC) Consisting of a Modified Camptothecin Payload Linked to an α<sub>V</sub>ß<sub>3</sub> Binder for the Treatment of Multiple Cancer TypesHans-Georg Lerchen, Beatrix Stelte-Ludwig, Charlotte Kopitz, et al.
The Journal of Organic Chemistry|December 10, 2019
A Selective Carborane-Functionalized Gastrin-Releasing Peptide Receptor Agonist as Boron Delivery Agent for Boron Neutron Capture TherapyPaul Hoppenz, Sylvia Els-Heindl, Martin Kellert, et al.
Cancers|September 9, 2023
Discovery of VIP236, an αvβ3-Targeted Small-Molecule-Drug Conjugate with Neutrophil Elastase-Mediated Activation of 7-Ethyl Camptothecin Payload for Treatment of Solid TumorsHans-Georg Lerchen, Beatrix Stelte-Ludwig, Melanie Heroult, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|March 15, 2019
Antibody-Prodrug Conjugates with KSP Inhibitors and Legumain-Mediated Metabolite FormationHans-Georg Lerchen, Beatrix Stelte-Ludwig, Sandra Berndt, et al.
Angewandte Chemie (International Ed. in English)|September 5, 2018
Antibody-Drug Conjugates with Pyrrole-Based KSP Inhibitors as the Payload ClassHans-Georg Lerchen, Sven Wittrock, Beatrix Stelte-Ludwig, et al.
Pageof 2